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New treatment option for Tibial Plateau Fractures
Official title Genicular Nerve Block After Open Reduction Internal Fixation of Tibial Plateau
ClinicalTrials.gov ID: NCT06639503
What this study is testing
What is Bupivacain?
Bupivacain is an investigational medicine, given as a pill taken by mouth, being studied as a potential treatment for tibial plateau fractures.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- The investigators are conducting this research study to find better ways of treating pain following knee surgery. There is a standard (accepted) approach, which involves injection of numbing medication into the area around the participant surgical incision.
- Phase 1: an early, usually small safety study
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- Any adult patient (ages 18 and over) undergoing open reduction internal fixation of an acute isolated tibial plateau fracture
You likely can't join if
- people younger than 18
- Polytraumatized people
- people with pathologic fractures
- people with tibial plateau fractures treated nonoperatively
- people with tibial plateau fractures treated operatively but with re-operations at the same site
- people with open fractures
See the full eligibility criteria
- Any adult patient (ages 18 and over) undergoing open reduction internal fixation of an acute isolated tibial plateau fracture
- people younger than 18
- Polytraumatized people
- people with pathologic fractures
- people with tibial plateau fractures treated nonoperatively
- people with tibial plateau fractures treated operatively but with re-operations at the same site
- people with open fractures
- people with fracture-dislocations
- people with active or history of anxiety
- people with visual analog scale anxiety score ≥ 7 measured preoperatively
- people with chronic pain syndromes
- people with chronic opioid use
- people with illicit drug use disorder
- people with alcohol abuse disorder
- people with kidney disease precluding use of ketorolac
- people with liver disease precluding the use of acetaminophen
- people with allergy to acetaminophen, non-steroidal anti-inflammatory drugs (NSAIDs), opiates or local anesthesia
- people with inability to provide a visual analog scale score postoperatively
- people with contraindications to receiving peripheral nerve blocks, including relevant neurologic deficits, active infection at sites of injections - re-operation at the same site
The study team makes the final eligibility decision.
Where it's taking place
- Chicago, Illinois, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Chicago, Illinois, United States. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.