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Tests treatment safety and results for Repeated IVF Failure
Official title Investigate the Efficacy of Using NMN to Improve Embryo Development Capacity.
ClinicalTrials.gov ID: NCT06629636
What this study is testing
- What it's testing
- The objective of this study is to investigate the efficacy of NMN supplementation in enhancing embryo developmental capacity and improving IVF success rates in patients experiencing IVF failures.
- You might receive a placebo (an inactive treatment) instead of the study drug, decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 32 to 42, women only
You may be able to join if
- Agree to participate in the study
- 32-42 years old
- Having at least one previous embryo implantation failure
- History of low Embryo quality at day3 or day5 (according to Veeck's and Gardner's Criteria)
- No major uterine or ovarian abnormalities
You likely can't join if
- Ovarian endometriosis with Chocolate cysts (AFS type 3 and 4)
- Patients who have taken different supplements such as coenzyme Q10, vitamin E, carnitine,niacin, nicotinamide, or other vitamin B3-related etc...
- Any medical contraindication of oocyte retrieval or subsequent procedures
- Couples where the husband presents with severe sperm abnormalities
- Couples where the husband presents \<5 million/mL motile sperm
- Uterine structural anomalies
See the full eligibility criteria
- Agree to participate in the study
- 32-42 years old
- Having at least one previous embryo implantation failure
- History of low Embryo quality at day3 or day5 (according to Veeck's and Gardner's Criteria)
- No major uterine or ovarian abnormalities
- BMI level 18-25kg/m2
- Ovarian endometriosis with Chocolate cysts (AFS type 3 and 4)
- Patients who have taken different supplements such as coenzyme Q10, vitamin E, carnitine,niacin, nicotinamide, or other vitamin B3-related etc. within the previous month
- Any medical contraindication of oocyte retrieval or subsequent procedures
- Couples where the husband presents with severe sperm abnormalities
- Couples where the husband presents \<5 million/mL motile sperm
- Uterine structural anomalies
- Polycystic ovaries
- Premature ovarian failure
- Individuals who need regular medication to treat chronic diseases such as diabetes, hypertension, gout, hyperuricemia, etc.
- Individuals who need drug treatment for any mental illness such as epilepsy and depression.
- Individuals who suffer from infectious diseases such as hepatitis B, active tuberculosis, AIDS, etc.
- Cancer patients or receiving chemo/radiotherapy treatment within the past 3 years.
The study team makes the final eligibility decision.
Where it's taking place
- Osaka, Osaka, Japan
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling female, 32 years to 42 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Osaka, Osaka, Japan. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.