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Compares treatment options for Protein Metabolism
Official title Prandial Metabolic Phenotyping in Sarcopenic Older Adults Comparing Plant Based and Whey Based Protein
ClinicalTrials.gov ID: NCT06628349
What this study is testing
- What it's testing
- The researchers overall objective is to determine whether plant and animal protein based proteins affect the anabolic responses across aging populations differently due to specific changes in the essential amino acids (EAA) and non-essential amino acids (NEAA) kinetic responses. The researchers central hypothesis is that a high EAA to NEAA ratio in a protein meal is related to higher anabolic response to the meal.
- You might receive a placebo (an inactive treatment) instead of the study drug.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 50 to 95. Healthy volunteers may be eligible.
You may be able to join if
- Age 50-95 years old
- Diagnosis of Chronic Obstructive Pulmonary Disease (COPD); COPD group only
- Stable body-weight (±5%) for the past 3 months
- Ability to walk, sit down, and stand up (independently or with walking assistance device)
- Willingness to lay supine in bed for up to 6 hours
You likely can't join if
- Established diagnosis and active treatment of chronic disease: Insulin dependent diabetes mellitus, active malignancy, heart disease, kidney disease...
- History of untreated metabolic disease including hepatic or renal disorder
- Presence of acute illness or metabolically unstable chronic illness
- Hysterectomy
- Active dependence of alcohol or drugs
- Use of short course of oral corticosteroids within 4 weeks preceding study day
See the full eligibility criteria
- Age 50-95 years old
- Diagnosis of Chronic Obstructive Pulmonary Disease (COPD); COPD group only
- Stable body-weight (±5%) for the past 3 months
- Ability to walk, sit down, and stand up (independently or with walking assistance device)
- Willingness to lay supine in bed for up to 6 hours
- Willingness and ability to comply with the protocol
- Established diagnosis and active treatment of chronic disease: Insulin dependent diabetes mellitus, active malignancy, heart disease, kidney disease, liver disease, HIV/AIDS, Asthma (moderate to severe), Hep (A,B, or C)
- History of untreated metabolic disease including hepatic or renal disorder
- Presence of acute illness or metabolically unstable chronic illness
- Hysterectomy
- Active dependence of alcohol or drugs
- Use of short course of oral corticosteroids within 4 weeks preceding study day
- Current use of long-term oral corticosteroids
- Use of protein or amino acids containing nutritional supplements within 5 days of the first study day
- Presence of fever within the last 3 days
- Planned elective surgery requiring 2 or more days of hospitalization during the entire study
- (Possible) pregnancy
- Failure to give informed consent or Investigator's uncertainty about the willingness or ability of the subject
- Already enrolled in another clinical trial
- Any condition according to the PI or nurse that was found during the screening visit, that would interfere with the study or safety of the patient
- Known allergy to any of the components of the feeding (soy, pea, or whey - dairy)
- Established daily diet of vegetarian / vegan composition
- \<23 MoCa score
The study team makes the final eligibility decision.
Where it's taking place
- College Station, Texas, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 50 years to 95 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include College Station, Texas, United States. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.