BridgeMD
Tests treatment safety and results for Dentin Hypersensitivity
Official title Efficacy of a Potassium Nitrate Containing Herbal Mouthwash to a Potassium Oxalate Mouthwash in Dentinal Hypersensitivity
ClinicalTrials.gov ID: NCT06627790
What this study is testing
What is Mouthwash preparation?
Mouthwash preparation is an investigational medicine, given as an once-daily pill taken by mouth, being studied as a potential treatment for dentin hypersensitivity.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- The goal of this clinical trial is to compare the efficacy of potassium nitrate containing herbal mouthwash to potassium oxalate mouthwash in management of dentinal hypersensitivity. Participants will be divided into two groups by computer generated randomization.
- Phase 3: a large, late-stage study
- This is a blinded study.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 60. Healthy volunteers may be eligible.
You may be able to join if
- Participants with at least two DH sites with VAS score ≥4
- Participants with teeth showing cervical abrasion, erosion, gingival recession
- Participants \>18 years in general good health
- Participants self-reporting with history of dentinal hypersensitivity to various stimuli.
- Participants with minimum 20 natural teeth
You likely can't join if
- Teeth with severe caries, faulty restoration, prosthetic crown, chipping, fracture, symptoms of pulpal damage
- Participants who has taken long term analgesic therapy within 30 days before the start of the study
- Participants who have undergone any treatment for dentinal hypersensitivity in past 3 months
- Participants with ongoing orthodontic therapy
- Participants with history or presence kidney disorder, kidney stones, eating disorders, uncontrolled gastro-oesophageal reflux disease, excessive...
- Severe Periodontal disease characterized by extensive tooth mobility and or extensive alveolar bone loss involving 10 or more teeth
See the full eligibility criteria
- Participants with at least two DH sites with VAS score ≥4
- Participants with teeth showing cervical abrasion, erosion, gingival recession
- Participants \>18 years in general good health
- Participants self-reporting with history of dentinal hypersensitivity to various stimuli.
- Participants with minimum 20 natural teeth
- Teeth with severe caries, faulty restoration, prosthetic crown, chipping, fracture, symptoms of pulpal damage
- Participants who has taken long term analgesic therapy within 30 days before the start of the study
- Participants who have undergone any treatment for dentinal hypersensitivity in past 3 months
- Participants with ongoing orthodontic therapy
- Participants with history or presence kidney disorder, kidney stones, eating disorders, uncontrolled gastro-oesophageal reflux disease, excessive exposure to acids or any other systemic condition that predisposes to...
- Severe Periodontal disease characterized by extensive tooth mobility and or extensive alveolar bone loss involving 10 or more teeth
- Women who are pregnant or lactating
The study team makes the final eligibility decision.
Where it's taking place
- Pune, Maharashtra, India
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 60 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Pune, Maharashtra, India. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.