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New treatment option for Renal Failure
Official title Prevent Cardiac Surgery Associated AKI Trial
ClinicalTrials.gov ID: NCT06620523
What this study is testing
What is CoQ10 1200 mg orally with Glutathione 1000 mg orally?
CoQ10 1200 mg orally with Glutathione 1000 mg orally is an investigational medicine, given as an once-daily, being studied as a potential treatment for renal failure.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- Prevent CSA-AKI (Cardiac Surgery Associated Acute Kidney Injury) trial is a double blinded randomized controlled trial, 242 patients undergoing elective cardiopulmonary bypass surgery (CPB)will either receive a placebo or daily 1200 mg of Co enzyme Q10 (CoQ10) and 1000 mg of Glutathione (GSH), the first dose will be given the day before surgery and continues while admitted up to 1 week. Blood and urine samples will be collected.
- Phase 2: a mid-size study of how well it works
- You might receive a placebo (an inactive treatment) instead of the study drug, decided by chance. You may not know which one you got.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 70
You may be able to join if
- Adult 18-70 years of age
- Undergoing elective CPB (Cardiopulmonary Bypass) surgery
- Baseline GFR (Glomerular Filtration Rate) ≥45 ml/min
You likely can't join if
- GFR (Glomerular Filtration Rate) \<45 ml/min
- Solitary kidney
- Status post-kidney transplant
- Pregnant women
- Allergy to CoQ10
- Allergy to Glutathione
See the full eligibility criteria
- Adult 18-70 years of age
- Undergoing elective CPB (Cardiopulmonary Bypass) surgery
- Baseline GFR (Glomerular Filtration Rate) ≥45 ml/min
- GFR (Glomerular Filtration Rate) \<45 ml/min
- Solitary kidney
- Status post-kidney transplant
- Pregnant women
- Allergy to CoQ10
- Allergy to Glutathione
- Allergy to Cellulose
The study team makes the final eligibility decision.
Where it's taking place
- Washington D.C., District of Columbia, United States
Compensation & support
Compensation mentioned.
ClinicalTrials.gov doesn't provide a reliable structured field for payment or travel support - confirm details with the study team.
Questions & answers
Do participants get paid in this trial?
This study's listing includes signals that participants may be compensated or receive a stipend. Amounts vary and are set by the study team - confirm the details with them.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 70 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Washington D.C., District of Columbia, United States. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.