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New treatment option for Renal Insufficiency, Chronic
Official title Time-restricted Eating in Patients With Moderate Chronic Kidney Disease and Albuminuria
ClinicalTrials.gov ID: NCT06618859
What this study is testing
- What it's testing
- Chronic kidney disease (CKD) affects approximately 12 to 15% of adults worldwide, with an increasing incidence expected. Major causes include diabetic nephropathy, hypertension, and various glomerulonephritis.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- Clinical criteria
- Adult men and women
- Chronic Kidney Disease with KDIGO stage G2 and G3 defined by a Glomerular Filtration Rate between 30 and 90 mL/min/1.73m2
- Albuminuria stage A2 or A3, but without nephrotic-range proteinuria: 3 to 200 mg/mmol
- Body mass index 18-40 kg/m2
You likely can't join if
- Clinical criteria
- Pregnant and breastfeeding women, plans for maternity during the study
- Eating disorder(s)
- Other diets: low-carb, ketogenic diet, hypocaloric diets (eviction for food intolerances, vegan/vegetarian diet are not excluded)
- Uncontrolled blood pressure (\> 160/100 mmHg)
- Diabetes with hypoglycemic drug(s) will be excluded, however those with impaired glucose tolerance (prediabetes, as defined by the American Diabetes...
See the full eligibility criteria
- Clinical criteria
- Adult men and women
- Chronic Kidney Disease with KDIGO stage G2 and G3 defined by a Glomerular Filtration Rate between 30 and 90 mL/min/1.73m2
- Albuminuria stage A2 or A3, but without nephrotic-range proteinuria: 3 to 200 mg/mmol
- Body mass index 18-40 kg/m2
- Eating window of 12 hours (self-reported and measured during the run-in phase)
- Study-related criteria
- Able to give informed consent and follow the study procedures for the entire duration
- Confident use of a smartphone compatible with the MyFoodRepo app (iOS, Android) and able to take regular pictures of food/drinks
- Clinical criteria
- Pregnant and breastfeeding women, plans for maternity during the study
- Eating disorder(s)
- Other diets: low-carb, ketogenic diet, hypocaloric diets (eviction for food intolerances, vegan/vegetarian diet are not excluded)
- Uncontrolled blood pressure (\> 160/100 mmHg)
- Diabetes with hypoglycemic drug(s) will be excluded, however those with impaired glucose tolerance (prediabetes, as defined by the American Diabetes Association) or diabetes with no risk of hypoglycemia (i.e. treated...
- Oral corticosteroids
- Uncontrolled diabetes HbA1c \> 8.5%
- Active cancer and/or oncologic treatment over the previous 12 months
- Major mental illness
- Consumption of \> 7 standard units of alcohol per week for women and \> 14 standard units of alcohol per week for men
- Shift work, such as evening shifts or night shifts planned during the study
- Travel/trip to a different time zone (≥ 2-hour time difference) planned during the study
- Study-related criteria and other interventions
- Recent treatment modification in the last 3 months, including but not limited to ACE blockers, SLGT2i, finerenone
- Patients with recent glomerulonephritis diagnosis on more than 2 immunosuppressive drugs
- Patients with kidney transplant in the last past year
- Enrolled in another treatment clinical trial (medication, medical device) over the previous 1 month and planned during the study
The study team makes the final eligibility decision.
Where it's taking place
- Geneva, Switzerland
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Geneva, Switzerland. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.