BridgeMD
New treatment option for Migraine With Aura
Official title Trial Designs for Evaluating Migraine Treatment
ClinicalTrials.gov ID: NCT06617832
What this study is testing
What is Active drug for acute migraine treatment?
Active drug for acute migraine treatment is an investigational medicine, given as a pill taken by mouth, being studied as a potential treatment for migraine with aura.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- The study aims to test interactions between drug and placebo-responses in acute migraine treatment and to assess variation in adverse events according to treatment information provided. Using a clinical within-subjects, advanced balanced placebo design, patients with episodic migraine will receive six treatment conditions in a randomized order.
- You might receive a placebo (an inactive treatment) instead of the study drug, decided by chance. You may not know which one you got.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 65
You may be able to join if
- Adults (18-65 years)
- ≥ 1-year history of migraine with or without aura according to the International Classification of Headache Disorders (ICHD-3) diagnostic criteria
- Known episodic migraine (≥ 1 and \ 3 months) with and without aura and diagnosed before age 50
- Previous or active use of triptans as acute treatment for migraine
- Ability to speak and read Danish
You likely can't join if
- Chronic migraine or history of chronic migraine in the last 12 months
- Other concomitant primary headache types except for infrequent tension-type headache
- Secondary headache disorders including medication overuse headache
- Severe psychiatric, vascular or liver diseases
- Opioid or barbiturate use in the month preceding screening
- Current use of preventive migraine treatment (i.e., onabotulinum toxin A, and/or Calcitonin gene-related peptide (CGRP) monoclonal antibodies)...
See the full eligibility criteria
- Adults (18-65 years)
- ≥ 1-year history of migraine with or without aura according to the International Classification of Headache Disorders (ICHD-3) diagnostic criteria
- Known episodic migraine (≥ 1 and \ 3 months) with and without aura and diagnosed before age 50
- Previous or active use of triptans as acute treatment for migraine
- Ability to speak and read Danish
- Chronic migraine or history of chronic migraine in the last 12 months
- Other concomitant primary headache types except for infrequent tension-type headache
- Secondary headache disorders including medication overuse headache
- Severe psychiatric, vascular or liver diseases
- Opioid or barbiturate use in the month preceding screening
- Current use of preventive migraine treatment (i.e., onabotulinum toxin A, and/or Calcitonin gene-related peptide (CGRP) monoclonal antibodies) (however, stable medical treatment with other migraine prophylactic agents...
- Contraindications or inability to tolerate triptans
- Current substance use disorder
- Implanted metallic or electronic device in the head
- Cardiac pacemaker or implanted or wearable defibrillator
- Use of illegal psychotropic drugs less than a week before participation in the study; regarding cannabis: less than four weeks before participation in the study
- Current pregnancy or planned pregnancy (confirmed by pregnancy test and by use of safe contraception as defined by the Danish Medicines Agency) and lactation
The study team makes the final eligibility decision.
Where it's taking place
- Aarhus C, Denmark
- Aarhus N, Denmark
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 65 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Aarhus C, Denmark; Aarhus N, Denmark. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.