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New treatment option for Tobacco Use
Official title Neural Mechanisms Connecting Deficient Sleep and Smoking Relapse
ClinicalTrials.gov ID: NCT06609369
What this study is testing
What is Varenicline?
Varenicline is an investigational medicine, given as an once-weekly, being studied as a potential treatment for tobacco use.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- The study aims to investigate whether behavioral interventions promote cessation in adult smokers by ameliorating negative emotions and improving self-control and identify the neural markers of these effects.
- Phase 2: a mid-size study of how well it works
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 65
You may be able to join if
- English literate
- report heavy tobacco use (including nicotine e-cigarettes) for \>6 months
- meet biochemical cut off for recent cigarette smoking or e-cigarette use
- optimal body mass index
You likely can't join if
- currently enrolled in other treatments
- neuropsychiatric exclusions that could interfere with study participation, increase risk of adverse events, and/or induce deficient sleep
- medical contraindications for fMRI, varenicline, and/or behavioral treatment
- factors that cause deficient sleep and for which behavioral treatment has less benefit
- women who are pregnant or nursing
The study team makes the final eligibility decision.
Where it's taking place
- New Haven, Connecticut, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 65 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include New Haven, Connecticut, United States. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.