BridgeMD
New treatment option for Hospital Acquired Pneumonia (HAP)
Official title Long-term Alterations of Host-microbiome Interactions and Cardiovascular and Respiratory Diseases Progression After Pneumonia
ClinicalTrials.gov ID: NCT06602934
What this study is testing
- What it's testing
- The HOMI-LUNG - HAP study is part of the HOMI-LUNG project, funded by the Horizon Europe program. The "HOMI-LUNG" project is an international, interdisciplinary project that aims to better understand the causal links between respiratory tract infections (i.e.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 80
You may be able to join if
- Group A (patients with acute cardiac disease)
- Male or female
- Hospitalized for acute coronary syndrome for less than 7 days.
- Informed consent from the patient
- Person insured under a health insurance scheme Group B (patients with chronic cardiovascular disease)
You likely can't join if
- Groups A, B, C and D
- Age \<80 years old
- Immunosuppression pre-existing to the index hospitalisation, defined as lymphopenia; 500 elements/mm3, haematologic cancer, aplasia...
- Pregnant women, breastfeeding women.
- Adults under guardianship or trusteeship.
- Low probability of survival at day 28. o Groups A, B, C
See the full eligibility criteria
- Group A (patients with acute cardiac disease)
- Male or female
- Hospitalized for acute coronary syndrome for less than 7 days.
- Informed consent from the patient
- Person insured under a health insurance scheme Group B (patients with chronic cardiovascular disease)
- Male or female,
- Undergoing coronary artery by-pass surgery
- Hospitalized in intensive care unit for \> 12 hours
- Informed consent from the patient
- Person insured under a health insurance scheme Group C (patients at risk of CVRD without chronic cardiovascular disease)
- Male or female,
- Familial high levels of cholesterol or triglycerides
- With no personal history of CVRD, with a recent negative cardiac exercise test (last test inferior to 12 months)
- Follow-up for lipid abnormalities at high risk of CVRD events
- Informed consent from the patient
- Person insured under a health insurance scheme Group D (patients with HAP)
- Male or female
- With one or more risk factors for CVD among: Age ≥ 65 years old Smoking, Abnormal lipidic levels, High blood pressure, Obesity, Diabetes mellitus, Chronic kidney disease
- Cured from mechanically ventilated HAP during the current hospitalization
- Informed consent from the patient or relatives
- Person insured under a health insurance scheme
- Groups A, B, C and D
- Age \<80 years old
- Immunosuppression pre-existing to the index hospitalisation, defined as lymphopenia; 500 elements/mm3, haematologic cancer, aplasia, chemotherapy/radiotherapy for cancer within 3 months prior to the inclusion, or...
- Pregnant women, breastfeeding women.
- Adults under guardianship or trusteeship.
- Low probability of survival at day 28. o Groups A, B, C
- Community-acquired pneumonia or Hospital-acquired pneumonia within the last year.
The study team makes the final eligibility decision.
Where it's taking place
- Angers, France
- Nantes, France
- Rennes, France
- Rouen, France
- Toulouse, France
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 80 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Angers, France; Nantes, France; Rennes, France; Rouen, France; Toulouse, France. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.