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New treatment option for Stroke
Official title Mapping Corticoreticulospinal Motor Control in Chronic Hemiparetic Stroke
ClinicalTrials.gov ID: NCT06598150
What this study is testing
- What it's testing
- This study uses functional magnetic resonance imaging to map neural activity throughout the central nervous system during a shoulder abduction task to characterize what motor pathways are being used post-stroke.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older. Healthy volunteers may be eligible.
You may be able to join if
- Adults aged at least 18y
- Able to perform shoulder abduction task (confirmed during screening and initial examination)
- Safe to undergo MRI
- Able to follow visual instructions using MRI-compatible vision correction goggles
- No brainstem or cerebellar lesions
You likely can't join if
- MRI contraindications
- Severe claustrophobia
- Pregnant women
- Prisoners
- Vulnerable populations
- Diagnosis/history of:
See the full eligibility criteria
- Adults aged at least 18y
- Able to perform shoulder abduction task (confirmed during screening and initial examination)
- Safe to undergo MRI
- Able to follow visual instructions using MRI-compatible vision correction goggles
- No brainstem or cerebellar lesions
- No severe concurrent medical problems
- Cognitive/attentional capacity to focus on a task
- Able to communicate in English or Spanish Additional for stroke participants:
- Have sustained only one unilateral subcortical, ischemic lesion in the territory supplied by the Middle Cerebral Artery (confirmed by clinical or radiological reports) at least one year prior to participation in this...
- Paresis confined to one side, with moderate-to-severe motor impairment of the upper limb (Upper Extremity Fugl-Meyer score between 10 and 45).
- MRI contraindications
- Severe claustrophobia
- Pregnant women
- Prisoners
- Vulnerable populations
- Diagnosis/history of:
- multiple sclerosis
- brain tumor
- brain radiation
- traumatic brain injury
- dementia
- Parkinson's disease
- Concurrent enrollment in an intervention study
- Concurrent use of medications known to suppress central nervous system activity
The study team makes the final eligibility decision.
Where it's taking place
- Chicago, Illinois, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Chicago, Illinois, United States. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.