BridgeMD
New treatment option for Alzheimer's Disease
Official title Effects of Combined 40 Hz Audio-visual Stimulation and Cognitive Games on Alzheimer's Disease
ClinicalTrials.gov ID: NCT06595511
What this study is testing
- What it's testing
- In addition to ongoing drug treatments for Alzheimer Disease (AD), protective approaches that can halt the progression of the disease are of particular importance. This project aims to develop a digital application that can monitor cognitive impairment, using EEG findings proven effective at the clinical level in Alzheimer and various types of dementia, including sensory entrainment and digital cognitive games.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 60 to 86. Healthy volunteers may be eligible.
You may be able to join if
- Inclusion and
You likely can't join if
- for Alzheimer Patients: Inclusion Criteria:
- Diagnosed with AD according to DSM-IV and NINCDS-ADRDA criteria,
- Impaired activities of daily living,
- Having a CDR score of 1-2 and an SMMT score of 15-26,
- Stable use of psychoactive medications, including acetylcholinesterase inhibitors or other medications that enhance cognitive functions,
- Individuals aged 60-86 with at least 5 years of education. Exclusion Criteria:
See the full eligibility criteria
- Inclusion and
- for Alzheimer Patients: Inclusion Criteria:
- Diagnosed with AD according to DSM-IV and NINCDS-ADRDA criteria,
- Impaired activities of daily living,
- Having a CDR score of 1-2 and an SMMT score of 15-26,
- Stable use of psychoactive medications, including acetylcholinesterase inhibitors or other medications that enhance cognitive functions,
- Individuals aged 60-86 with at least 5 years of education. Exclusion Criteria:
- Having frontotemporal dementia, vascular dementia, Lewy body dementia or other types of dementia,
- Parkinsonism, clinical depression, other mental disorders, epilepsy, drug addiction, alcohol addiction, and traumatic brain injury Inclusion and Exclusion Criteria of Healthy Older Adults: Inclusion criteria:
- Between the ages of 60-86
- Without any neurological abnormalities or general cognitive impairment (MMSE above 25),
- Not diagnosed with a neurological and/or psychiatric disease,
- Not using neurological and/or psychiatric medication Exclusion criteria
- Having clinical signs of cognitive impairment, such as mild cognitive impairment, Alzheimer disease, Parkinson disease, Lewy body dementia, frontotemporal dementia, etc.
- Epilepsy, alcohol and/or drug addiction, use of medications that affect cognitive functions, and traumatic brain injury
The study team makes the final eligibility decision.
Where it's taking place
- Istanbul, Beykoz, Turkey (Türkiye)
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 60 years to 86 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Istanbul, Beykoz, Turkey (Türkiye). Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.