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New treatment option for Older Adults
Official title Black Rice Consumption on Cognitive Function, Inflammation and Microvascular Function in Older Adults
ClinicalTrials.gov ID: NCT06583785
What this study is testing
- What it's testing
- Cognitive (brain) function, especially memory, gradually declines during ageing, which may in part be caused by an increase in systemic inflammation as well as a reduction in vascular functions and cerebral blood flow. Blood inflammatory mediators such as c-reactive protein (CRP) and interleukin-6 (IL-6) found to be significantly higher among people over 65 years compared to younger age groups.
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 50 to 80. Healthy volunteers may be eligible.
You may be able to join if
- Aged 50-80 years
- General healthy status
- Body Mass Index (BMI)18.5-35 kg/m2
You likely can't join if
- Taking anti-inflammatory drugs (e.g., aspirin, warfarin, ibuprofen)
- Having sign of infections or acute inflammation (e.g., fever, chills, sore throat, nasal congestion, moderate-severe pain, swelling-redness)
- Received antibiotics within the past 3 months
- Taking dietary supplements (e.g., vitamins, minerals) at high doses (e.g., more than 200% of the UK's reference nutrient intakes)
- Taking hormone replacement therapy, if you are menopausal
- Had major surgery (head, heart, chest, abdomen) within the past 6 months.
See the full eligibility criteria
- Aged 50-80 years
- General healthy status
- Body Mass Index (BMI)18.5-35 kg/m2
- Taking anti-inflammatory drugs (e.g., aspirin, warfarin, ibuprofen)
- Having sign of infections or acute inflammation (e.g., fever, chills, sore throat, nasal congestion, moderate-severe pain, swelling-redness)
- Received antibiotics within the past 3 months
- Taking dietary supplements (e.g., vitamins, minerals) at high doses (e.g., more than 200% of the UK's reference nutrient intakes)
- Taking hormone replacement therapy, if you are menopausal
- Had major surgery (head, heart, chest, abdomen) within the past 6 months.
- Having plan to start to a restricted diet/ changing dietary pattern or lose weight.
- Diagnosed with neurodegenerative diseases (e.g., Dementia, Alzheimer's, Parkinson's, current stroke)
- Diagnosed with psychotic disorders (e.g., schizophrenia, bipolar depression, eating disorder)
- Diagnosed with cardiovascular disease, diabetes, hyperlipidemia, hypertension (blood pressure\>140/90 mmHg), active cancer, liver, or kidney diseases.
- Taking medication to lower blood fats (e.g., statins, fibrates) or to stabilise blood glucose (e.g., acarbose, metformin or sulfonylureas) or lower blood pressure.
- Unable to complete the cognitive function tasks for any reason (i.e., visual impairments, hearing loss)
- If you have a peacemaker
- If you have bleeding disorders or blood related diseases (anaemia, thalassemia, thrombosis, embolism)
- Heavy smoker
- Heavy alcohol drinking (\> 14 units/week) or a history of alcohol/substance abuse
- Allergies, hypersensitivity, or food intolerances (rice, eggs, soy sauce, vegetable oil)
The study team makes the final eligibility decision.
Where it's taking place
- Reading, UK, United Kingdom
- Reading, United Kingdom
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 50 years to 80 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Reading, UK, United Kingdom; Reading, United Kingdom. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.