BridgeMD
New treatment option for Cannabis Use
Official title Cannabis, Linked Emotions, and Adolescent Risk Study
ClinicalTrials.gov ID: NCT06576076
What this study is testing
- What it's testing
- The goal of this study is to disentangle relationships between acute cannabis use and withdrawal on proximal depression and suicide risk and recovery in adolescents ages 12-18 years by incorporating time-varying patterns of substance use, mood, and SI. This project aims to guide the development of scalable, individualized, accessible, and affordable interventions aimed to reduce depression and suicide risk among adolescents.
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 12 to 18
You may be able to join if
- Ages 12-18;
- Current daily or near daily cannabis use (i.e., use ≥ 4 days per week on average; Timeline Followback);
- Score ≥ 5 on PHQ-9;
- Access to an internet-capable smartphone (iOS or Android);
- Provision of at least 1 collateral contact for risk monitoring;
You likely can't join if
- Any factor that impairs ability to comprehend and effectively participate, including acute intoxication at time of consent;
- Cannabis use \>4 times/day on average (to maximize likelihood of capturing mood and SI during non-use times);
- Inability to speak/write English fluently;
- Gross cognitive impairment, for example due to florid psychosis, intellectual disability, developmental delay, or neurodegenerative disease;
- Current epilepsy diagnosis;
- Individuals who are under the legal protection of the government or state (wards of the state);
See the full eligibility criteria
- Ages 12-18;
- Current daily or near daily cannabis use (i.e., use ≥ 4 days per week on average; Timeline Followback);
- Score ≥ 5 on PHQ-9;
- Access to an internet-capable smartphone (iOS or Android);
- Provision of at least 1 collateral contact for risk monitoring;
- Provision of informed assent (or consent if 18 years or older) and parent/guardian consent if \<age 18;
- Greater than 50% response rate to EMA prompts during the first EMA phase;
- No immediate plan to discontinue cannabis use in the next 3 months;
- Positive toxicology result for cannabis on baseline urinalysis.
- Any factor that impairs ability to comprehend and effectively participate, including acute intoxication at time of consent;
- Cannabis use \>4 times/day on average (to maximize likelihood of capturing mood and SI during non-use times);
- Inability to speak/write English fluently;
- Gross cognitive impairment, for example due to florid psychosis, intellectual disability, developmental delay, or neurodegenerative disease;
- Current epilepsy diagnosis;
- Individuals who are under the legal protection of the government or state (wards of the state);
- Response of "No" to the knowledge check question regarding EMA suicidality response time;
- Inability to wear Fitbit device.
The study team makes the final eligibility decision.
Where it's taking place
- Boston, Massachusetts, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 12 years to 18 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Boston, Massachusetts, United States. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.