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New treatment option for Labor Pain
Official title Quality of Labour Epidural Analgesia With Intrathecal Morphine as a Component of Combined Spinal Epidural
ClinicalTrials.gov ID: NCT06572241
What this study is testing
What is Intrathecal morphine?
Intrathecal morphine is an investigational medicine, given as an infusion into a vein, being studied as a potential treatment for labor pain.
Also referred to as Morphine.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- Neuraxial analgesia has shown to be the gold standard for effective labor pain relief, offering numerous benefits including enhanced pain control and maternal satisfaction. The methods to achieve neuraxial analgesia include lumbar epidural (LE), and combined spinal epidural (CSE).
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 50, women only. Healthy volunteers may be eligible.
You may be able to join if
- Adult (≥18 years) term primiparous (≥37 weeks) patients with live singleton pregnancy
- Patients who request labour analgesia and do not have any contraindications for neuraxial analgesia.
- Less than or equal to 6 cm cervical dilation during the last vaginal examination.
You likely can't join if
- Patients who are expected to be discharged within 24 hours of delivery.
- Patients with chronic pain conditions, opioid use disorder, pre-gestational diabetes, obstructive sleep apnea, morbid obesity (BMI \>40 kg/m2), or...
- Patients who have intramuscular morphine within 12 hours or fentanyl \>200 mcg in the preceding 4 hours.
- Participants will be excluded from further analysis in case of spinal analgesic failure
- Participants will be excluded from further analysis if labour lasts less than 2 hours
The study team makes the final eligibility decision.
Where it's taking place
- Toronto, Ontario, Canada
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling female, 18 years to 50 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Toronto, Ontario, Canada. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.