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New treatment option for Constipation
Official title Levofloxacin in the Treatment of Chronic Functional Constipation Associated With PIB(Peristaltic Contraction-Inhibiting Bacterium) Infection
ClinicalTrials.gov ID: NCT06571097
What this study is testing
What is Levofloxacin?
Levofloxacin is an investigational medicine, given as a treatment applied to the skin, being studied as a potential treatment for constipation.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- Constipation, a prevalent clinical condition, significantly impacts patients' quality of life, yet relevant clinical trial technical guidelines have yet to be issued domestically. This disease encompasses various classifications based on etiology, pathology, and pathophysiological characteristics.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 70. Healthy volunteers may be eligible.
You may be able to join if
- Participants must meet all of the following criteria to enter the trial.
- Signed written informed consent;
- Age 18-70;
- Diagnosed chronic functional constipation according to Rome III or IV criteria, and infected with PIB;
- Patients who have not taken other types of antibiotics in the past 1 month;
You likely can't join if
- Exclusion criteria: people must exclude all of the following conditions to enter the study.
- Pregnant and lactating women;
- Patients with drug-induced constipation, including constipation induced by opioids and antidepressants;
- During the study period, changes in lifestyle and dietary habits are not recommended in principle;
- Patients with diseases that affect the conduct or results of the study, such as mental illness, serious cardiopulmonary, liver and kidney diseases...
- Those who cannot take samples and complete inspection items as required;
See the full eligibility criteria
- Participants must meet all of the following criteria to enter the trial.
- Signed written informed consent;
- Age 18-70;
- Diagnosed chronic functional constipation according to Rome III or IV criteria, and infected with PIB;
- Patients who have not taken other types of antibiotics in the past 1 month;
- Bowel organic lesions (tumors and severe inflammatory lesions, etc.) were excluded by colonoscopy in the past 2 years.
- The people could follow the follow-up plan, objectively describe the symptoms, and cooperate with the completion of the scale; 7）Agree to maintain similar diet and activity levels from the screening visit to the end of...
- Exclusion criteria: people must exclude all of the following conditions to enter the study.
- Pregnant and lactating women;
- Patients with drug-induced constipation, including constipation induced by opioids and antidepressants;
- During the study period, changes in lifestyle and dietary habits are not recommended in principle;
- Patients with diseases that affect the conduct or results of the study, such as mental illness, serious cardiopulmonary, liver and kidney diseases, history of gastrointestinal surgery, epilepsy, etc.
- Those who cannot take samples and complete inspection items as required;
- Allergic to levofloxacin; 7）Other researchers found it inappropriate to participate in the project for clinical manifestations or diseases.
The study team makes the final eligibility decision.
Where it's taking place
- Nanjing, Jiangsu, China
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 70 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Nanjing, Jiangsu, China. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.