BridgeMD
Compares treatment options for Effect of Drug
Official title Comparing Trypsin-Chymotrypsin and Naproxen Sodium for Post-endodontic Treatment Pain
ClinicalTrials.gov ID: NCT06562816
What this study is testing
What is Trypsin-Chymotrypsin?
Trypsin-Chymotrypsin is an investigational medicine, given as an infusion into a vein, being studied as a potential treatment for effect of drug.
Also referred to as Chymoral Forte.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- This study aims to compare the pain reduction efficacy of Trypsin-Chymotrypsin and Naproxen sodium after root canal treatment in patients with symptomatic irreversible pulpitis. A lot of patients suffer greatly from post endodontic treatment pain and have a fear of dental treatments due to the pain.
- Phase 4: studies an already-approved treatment
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 45. Healthy volunteers may be eligible.
You may be able to join if
- Both male and female, healthy patients (ASA class 1).
- Patients between the age group of 18-45 years.
- Patients who are appointed for endodontic treatment.
- Maxillary or mandibular teeth diagnosed with symptomatic irreversible pulpitis based on delayed responses to vitality tests.
You likely can't join if
- Patients who will require emergency dental treatment.
- Teeth with any form of peri-apical lesion will be excluded.
- Patient who have taken analgesics within 24 hours prior to the treatment.
- Patients with known hypersensitivity or allergy to any of the study medications.
- Patients with any systemic disease such as uncontrolled diabetes, gastric ulcers, bleeding disorders, or cardiovascular problems.
- Pregnant or lactating women and pediatric patients.
The study team makes the final eligibility decision.
Where it's taking place
- Karachi, Sindh, Pakistan
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 45 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Karachi, Sindh, Pakistan. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.