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Tests treatment safety and results for Helicobacter Pylori Infection
Official title Clinical Study to Evaluate the Possible Efficacy and Safety of Diosmin and Hesperidin Combined Therapy in Patients With Helicobacter Pylori Infection
ClinicalTrials.gov ID: NCT06546111
What this study is testing
What is Daflon?
Daflon is an investigational medicine, being studied as a potential treatment for helicobacter pylori infection.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- This study intends to assess the possible effectiveness and safety of Diosmin and Hesperidin combination in patients with Helicobacter pylori Infection through evaluating its effect on stool antigen test and serum levels of inflammatory biomarkers as(TNF-A and MDA).
- Phase 2: a mid-size study of how well it works
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 75
You may be able to join if
- Confirmed H. pylori infection through stool antigen test.
- Patients did not receive prior eradication therapy.
- Male and female.
- Age of 18-75 years old.
- Good mental well-being to clearly understand the study's objectives, advantages and procedures.
You likely can't join if
- Age less than 18 years.
- Patients with previous H. pylori eradication therapy.
- Patients with hypersensitivity/allergy to the study medications.
- Patients with history of using proton pump inhibitor, H2-blocker, antibiotics that affect H. pylori in the last month.
- Patients with history of using diosmin and/or hesperidin in the last month.
- Patients with history of gastric tumor or gastrointestinal (GI) surgery.
See the full eligibility criteria
- Confirmed H. pylori infection through stool antigen test.
- Patients did not receive prior eradication therapy.
- Male and female.
- Age of 18-75 years old.
- Good mental well-being to clearly understand the study's objectives, advantages and procedures.
- Age less than 18 years.
- Patients with previous H. pylori eradication therapy.
- Patients with hypersensitivity/allergy to the study medications.
- Patients with history of using proton pump inhibitor, H2-blocker, antibiotics that affect H. pylori in the last month.
- Patients with history of using diosmin and/or hesperidin in the last month.
- Patients with history of gastric tumor or gastrointestinal (GI) surgery.
- Patients with concomitant severe disorders; cardiovascular, pulmonary, renal or hepatic, or active malignancy.
- Pregnancy or breastfeeding.
- History of drug misuse or recent alcohol consumption.
- Patients with gall bladder disorders.
- Patients on blood thinning agents (warfarin, clopidogril, aspirin, etc), anticonvulsants (carbamazepine and phenytoin), muscle relaxants (chlorzoxazone) and NSAID (diclofenac) in order to avoid potential pharmacodynamic...
- Patients on anti-inflammatory drugs and antioxidant drugs.
- Patients with inflammatory conditions (ulcerative colitis, rheumatoid arthritis, etc.).
- Patients with conditions associated with oxidative stress (smoking, COPD, etc.).
The study team makes the final eligibility decision.
Where it's taking place
- Shibīn al Kawm, Egypt
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 75 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Shibīn al Kawm, Egypt. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.