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New treatment option for Pancreatic Cancer
Official title Clinical Study Evaluating the Effect of Losartan
ClinicalTrials.gov ID: NCT06539806
What this study is testing
What is Losartan 50mg Tab?
Losartan 50mg Tab is an investigational medicine, being studied as a potential treatment for pancreatic cancer.
Also referred to as Gemcitabine hydrochloride.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- The pancreas is two organs packaged into one. The islets of Langerhans serve critical endocrine functions, and the exocrine portion is a major source of enzymes that are essential for digestion.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 50 to 85
You may be able to join if
- Male and female pancreatic cancer patients aged ≥ 50 years old.
- Hypertensive patient with BP ≥ 140/90 mm Hg.
- Histologically confirmed metastatic pancreatic adenocarcinoma; or locally advanced pancreatic cancer patients.
- All included patients must sign an informed consent
You likely can't join if
- Patients with serious concomitant systemic disorders as significant cardiac, renal, hepatic, or pulmonary morbidity.
- Pregnant or lactating women and women of childbearing potential.
- Patients received prior systemic fluoropyrimidine therapy within the past 10 years.
- Prior un-anticipated severe reaction to fluoropyrimidine therapy, or known hypersensitivity to 5-fluorouracil, irinotecan, oxaliplatin, losartan, or...
- Patients with an active, known, or suspected autoimmune disease such as psoriasis.
- Patients with a known positive test for hepatitis B virus surface antigen (HBV s Ag) or hepatitis C virus (HCV antibody) and patients with a known...
See the full eligibility criteria
- Male and female pancreatic cancer patients aged ≥ 50 years old.
- Hypertensive patient with BP ≥ 140/90 mm Hg.
- Histologically confirmed metastatic pancreatic adenocarcinoma; or locally advanced pancreatic cancer patients.
- All included patients must sign an informed consent
- Patients with serious concomitant systemic disorders as significant cardiac, renal, hepatic, or pulmonary morbidity.
- Pregnant or lactating women and women of childbearing potential.
- Patients received prior systemic fluoropyrimidine therapy within the past 10 years.
- Prior un-anticipated severe reaction to fluoropyrimidine therapy, or known hypersensitivity to 5-fluorouracil, irinotecan, oxaliplatin, losartan, or any monoclonal antibody.
- Patients with an active, known, or suspected autoimmune disease such as psoriasis.
- Patients with a known positive test for hepatitis B virus surface antigen (HBV s Ag) or hepatitis C virus (HCV antibody) and patients with a known history of testing positive for (HIV) or known acquired immunodeficiency...
- Patients received a live vaccine or live attenuated vaccines as intranasal influenza vaccines within 30 days of the planned start of study therapy.
The study team makes the final eligibility decision.
Where it's taking place
- Tanta, Egypt
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 50 years to 85 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Tanta, Egypt. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.