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New treatment option for Anesthesia
Official title Anesthesia Induction with the Target-controlled Infusion of Propofol in High-risk Patients
ClinicalTrials.gov ID: NCT06535230
What this study is testing
What is Manual anesthesia induction?
Manual anesthesia induction is an investigational medicine, given as an infusion into a vein, being studied as a potential treatment for anesthesia.
Also referred to as Manuel induction.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- The purpose of this study is to compare the risk of hypotension following induction of anesthesia in high-risk patients (American Society of Anesthesiologists risk scores III and IV) using target-controlled infusion (TCI) of propofol versus standard manual induction of anesthesia. Our previously published study compared TCI and manual induction of anesthesia in a general patient population and found that hypotension developed less with TCI induction.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 100
You may be able to join if
- Patients with the American Society of Anesthesiology physical status 3-4
- Underwent major elective surgery
- Required intra-arterial blood pressure monitoring before induction.
You likely can't join if
- Under 18 years of age
- Patients with the American Society of Anesthesiology physical status 1-2
- Arrhythmia (atrial fibrillation, frequent premature beat)
- Severe valvular heart disease
- Morbid obesity
- Intubation difficulty
See the full eligibility criteria
- Patients with the American Society of Anesthesiology physical status 3-4
- Underwent major elective surgery
- Required intra-arterial blood pressure monitoring before induction.
- Under 18 years of age
- Patients with the American Society of Anesthesiology physical status 1-2
- Arrhythmia (atrial fibrillation, frequent premature beat)
- Severe valvular heart disease
- Morbid obesity
- Intubation difficulty
- Drug addiction
- Treatment with opiates
- Pregnancy
- Emergency surgery
The study team makes the final eligibility decision.
Where it's taking place
- Istanbul, Turkey (Türkiye)
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 100 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Istanbul, Turkey (Türkiye). Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.