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Tests treatment safety and results for Enterococcus Faecalis Infection
Official title Antimicrobial Efficacy of Nano-Based ICM on E.F
ClinicalTrials.gov ID: NCT06533215
What this study is testing
- What it's testing
- This in-vivo study aims to evaluate the antimicrobial effect of nano based intracanal medications (Triple antibiotic-loaded chitosan nanoparticles and chlorohexidine loaded by silver nanoparticles) on Enterococcus faecalis count reduction in secondary endodontic infection cases.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 19 to 60. Healthy volunteers may be eligible.
You may be able to join if
- Single rooted, single canal premolar teeth.
- Teeth indicated for non-surgical root canal retreatment.
- Teeth have signs and/or symptoms of post-treatment disease manifested by recurrent acute and/or chronic periapical abscess.
- Teeth have clinical signs and symptoms of endodontic failure as sensitivity to percussion, pain, swelling or fistula.
- Teeth with radiographic features of endodontic failure as persistent periapical lesion or widening of periodontal ligament.
You likely can't join if
- Patients with any systemic diseases.
- Pregnant or lactating patients.
- Immunocompromised patients.
- Non-restorable tooth.
- Calcified root canal.
- Teeth with root fracture.
See the full eligibility criteria
- Single rooted, single canal premolar teeth.
- Teeth indicated for non-surgical root canal retreatment.
- Teeth have signs and/or symptoms of post-treatment disease manifested by recurrent acute and/or chronic periapical abscess.
- Teeth have clinical signs and symptoms of endodontic failure as sensitivity to percussion, pain, swelling or fistula.
- Teeth with radiographic features of endodontic failure as persistent periapical lesion or widening of periodontal ligament.
- Symptomatic or asymptomatic teeth with short root canal filling indicated for prosthetic restoration
- Patients with any systemic diseases.
- Pregnant or lactating patients.
- Immunocompromised patients.
- Non-restorable tooth.
- Calcified root canal.
- Teeth with root fracture.
- Teeth with periodontal pocket deeper than 4mm.
- Teeth have procedural error like ledge, broken instrument, or perforation
The study team makes the final eligibility decision.
Where it's taking place
- Tanta, Egypt
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 19 years to 60 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Tanta, Egypt. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.