BridgeMD
New treatment option for Anorexia
Official title Olanzapine for Cancer Related Anorexia-cachexia Syndrome
ClinicalTrials.gov ID: NCT06517199
What this study is testing
What is Olanzapine 2.5 MG?
Olanzapine 2.5 MG is an investigational medicine, being studied as a potential treatment for anorexia.
Also referred to as OLN2.5.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- Cancer anorexia-cachexia syndrome is one of the common conditions in cancer patients. Olanzapine has been demonstrated to reduce chemotherapy-induced anorexia.
- Phase 3: a large, late-stage study
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- pathologically or cytologically metastatic or locally advanced cancer
- anorexia and \>=5% weight loss during the past 6 months or anorexia with numerical scale of anorexia \>=5
- ECOG performance status 0-3
- able to complete questionaire and able to swallow pills
You likely can't join if
- receiving chemotherapy or anti-cancer systemic therapy
- life expectancy longer than 1 month
- received radiotherapy at head/neck or thoracic or upper abdomen in the past 2 weeks
- surgery within 4 weeks
- pregnancy
- serum bilirubin \> 2 mg/dl or serum Cr \> 2 mg/dl
See the full eligibility criteria
- pathologically or cytologically metastatic or locally advanced cancer
- anorexia and \>=5% weight loss during the past 6 months or anorexia with numerical scale of anorexia \>=5
- ECOG performance status 0-3
- able to complete questionaire and able to swallow pills
- receiving chemotherapy or anti-cancer systemic therapy
- life expectancy longer than 1 month
- received radiotherapy at head/neck or thoracic or upper abdomen in the past 2 weeks
- surgery within 4 weeks
- pregnancy
- serum bilirubin \> 2 mg/dl or serum Cr \> 2 mg/dl
- current use of olanzapine or other antipsychotic drug
- known cardiac arrhythmia, uncontrolled brain metastasis, history of seizure or acute coronary event in the past 6 months
The study team makes the final eligibility decision.
Where it's taking place
- Bangkok, Thailand
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Bangkok, Thailand. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.