BridgeMD
New treatment option for Fungal Infection
Official title Pharmacogenomics for Better Treatment of Fungal Infections Clinical Trial
ClinicalTrials.gov ID: NCT06510699
What this study is testing
- What it's testing
- This project aims to address invasive fungal infections in patients, by precision dosing of voriconazole based on CYP2C19 genotype testing with Bayesian dose-forecasting dosing software to develop patient-centric and maximally effective dosing regimens. This study investigates if voriconazole increases the proportion of patients achieving therapeutic exposure at day 8 of dosing compared with standard care; and will assess factors that influence the implementation of genotype testing and dosing software in the healthcare system, including fidelity, feasibility, acceptability and cost-effectiveness.
- Phase 2: a mid-size study of how well it works
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 2 and older. Healthy volunteers may be eligible.
You may be able to join if
- Age ≥ 2 years.
- Written informed consent obtained.
- Decision to prescribe voriconazole.
- Admitted to a trial site, or sufficient outpatient follow-up appointments are feasible
You likely can't join if
- Post-allogeneic haematopoietic stem cell transplant (HCT) patient, without access to pre HCT DNA
- Death is likely imminent within 7 days.
- Previously assigned by chance to this trial
The study team makes the final eligibility decision.
Where it's taking place
- Seattle, Washington, United States
- Sydney, New South Wales, Australia
- Brisbane, Queensland, Australia
- South Brisbane, Queensland, Australia
- Adelaide, South Australia, Australia
- Melbourne, Victoria, Australia
Compensation & support
Compensation mentioned.
ClinicalTrials.gov doesn't provide a reliable structured field for payment or travel support - confirm details with the study team.
Questions & answers
Do participants get paid in this trial?
This study's listing includes signals that participants may be compensated or receive a stipend. Amounts vary and are set by the study team - confirm the details with them.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 2 years and older. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Seattle, Washington, United States; Sydney, New South Wales, Australia; Brisbane, Queensland, Australia; South Brisbane, Queensland, Australia; Adelaide, South Australia, Australia; Melbourne, Victoria, Australia. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.