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New treatment option for Time Restricted Eating
Official title Time-restricted Eating and Cognition
ClinicalTrials.gov ID: NCT06508255
What this study is testing
- What it's testing
- This study aims to investigate how time-restricted eating (TRE), more specifically TRE at different times (early vs late in the day), influences brain activity, behavior, decision-making, food intake, physical activity, the gut microbiome and metabolic processes. The study intervention procedure is a replication of that described in Peters et al.
- Time commitment: about 8 weeks
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 70, women only. Healthy volunteers may be eligible.
You may be able to join if
- right-handed
- legally competent
- physically and mentally healthy
- BMI: 19-35 kg/m²
- fluent in reading and speaking German
You likely can't join if
- weight change \>5% of body weight during the last 3 months
- pregnancy or breastfeeding
- allergies (inclusion possible after consultation with study doctor)
- history of cardiovascular disease (myocardial infarction, stroke, hypertension, hypotension) in the last year
- severe psychiatric condition, including drug addiction and depression
- impaired renal or liver function
See the full eligibility criteria
- right-handed
- legally competent
- physically and mentally healthy
- BMI: 19-35 kg/m²
- fluent in reading and speaking German
- weight change \>5% of body weight during the last 3 months
- pregnancy or breastfeeding
- allergies (inclusion possible after consultation with study doctor)
- history of cardiovascular disease (myocardial infarction, stroke, hypertension, hypotension) in the last year
- severe psychiatric condition, including drug addiction and depression
- impaired renal or liver function
- dementia or other severely debilitating cognitive disease
- history of or current eating disorders (e.g., Bulimia nervosa, Anorexia nervosa, Orthorexia nervosa, Binge-Eating disorder)
- chronic diseases (e.g., Morbus Crohn, Colitis Ulcerosa)
- metabolic disorders (e.g., metabolic syndrome, diabetes type 1 or 2)
- hormonal imbalances (e.g., thyroid gland diseases)
- consuming diseases (e.g., cancer, kachexie) in the last 2 years
- surgical removal (partial removal) of the digestive organs (e.g., gastrectomy) or history of bariatric surgery
- Autoimmune conditions or current infection
- Blood clotting disorders (e.g., haemophilia)
- Severe anemia
- severe claustrophobia
- blood donation four weeks prior to study entry
- glucocorticoid therapy (oral)
- anticoagulant medication (inclusion possible if medication can be paused)
- taking medications that require regular eating
- any medications or supplements known to affect sleep, circadian rhythms, immune activity or metabolism
- taking weight loss, lipid or glucose-lowering medications (any medications that affects metabolism) i.e. metformin
- pacemaker or other electrical implant
- vaccination during the study course or in the two weeks' prior
- immunosuppressive premedication
- currently on a diet/fasting regime (or within 1 month)
- professional athletes
- nicotine consumption
- drug abuse
- alcohol consumption per week more than 14 beers (0,3l)/ wine (0,125l)/ sparkling wine (0,1l)/Schnaps (4cl)
- shift work
- poor sleep quality (PSQI score \> 10 at medical screening)
- travel across more than one time zone one month before study or during study period
- non-removable metallic implants
- fear of blood draw
The study team makes the final eligibility decision.
Where it's taking place
- Nuthetal, Germany
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The study runs about 8 weeks per participant, based on its public description. The team confirms the exact schedule and number of visits before you enroll.
Who can join this trial?
This study is enrolling female, 18 years to 70 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Nuthetal, Germany. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.