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Compares treatment options for Cervical Preparation
Official title Mifepristone vs Misoprostol
ClinicalTrials.gov ID: NCT06502158
What this study is testing
What is Mifepristone?
Mifepristone is an investigational medicine, being studied as a potential treatment for cervical preparation.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- The Investigator team hypothesizes that in a randomized trial comparing mifepristone-alone or misoprostol-alone for cervical preparation for procedural abortions at 12 to 16 weeks in hospital-based care, the proportion of patients who achieve successful cervical dilation will be different between the study groups.
- Phase 1: an early, usually small safety study
- Time commitment: about 16 weeks
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 45, women only. Healthy volunteers may be eligible.
You may be able to join if
- English or Spanish-speaking
- Capacity to consent
- Seeking induced abortion of a singleton pregnancy
- Between 12 weeks, 0 days and 16 weeks, 6 days (based on age at day of surgery)
You likely can't join if
- History of more than two prior Cesarean deliveries
- Sonographic evidence of placenta previa
- Sonographic concern for morbidly adherent placenta
- Prior obstetric hemorrhage requiring transfusion
- Obstructive cervical or lower uterine segment fibroid
- Current therapeutic anticoagulation use
See the full eligibility criteria
- English or Spanish-speaking
- Capacity to consent
- Seeking induced abortion of a singleton pregnancy
- Between 12 weeks, 0 days and 16 weeks, 6 days (based on age at day of surgery)
- History of more than two prior Cesarean deliveries
- Sonographic evidence of placenta previa
- Sonographic concern for morbidly adherent placenta
- Prior obstetric hemorrhage requiring transfusion
- Obstructive cervical or lower uterine segment fibroid
- Current therapeutic anticoagulation use
- Cerclage in situ
- History of more than one prior cervical excisional procedure
- BMI greater than 50 kg/m\^2
The study team makes the final eligibility decision.
Where it's taking place
- The Bronx, New York, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The study runs about 16 weeks per participant, based on its public description. The team confirms the exact schedule and number of visits before you enroll.
Who can join this trial?
This study is enrolling female, 18 years to 45 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include The Bronx, New York, United States. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.