Recruiting EARLY_PHASE1 Electronic Cigarette Use

New treatment option for Electronic Cigarette Use

Official title Role of Inflammation in Vascular Phenotype Associated With E-cigarette Use

ClinicalTrials.gov ID: NCT06489249

What this study is testing

What is Salsalate 750 MG Oral Tablet [DISALCID]?

Salsalate 750 MG Oral Tablet [DISALCID] is an investigational medicine, given as a pill taken by mouth, being studied as a potential treatment for electronic cigarette use.

Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.

What it's testing
The use of electronic nicotine delivery systems, or e-cigarettes - colloquially referred to as "vaping" - in the United States has increased exponentially since their introduction to the US market in 2007. Prevalence of ever and current e-cigarette use is highest among teenagers and young adults with 16-28% of this population having reported vaping.
  • Phase 1: an early, usually small safety study

A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.

Who can take part

Ages 18 to 24. Healthy volunteers may be eligible.

You may be able to join if

  • 18 - 24 years of age
  • no history of e-cigarette use (control) OR current with 6 months or more history of e-cigarette use (chronic use).

You likely can't join if

  • tobacco cigarette use (current or history of)
  • use of stimulant drugs
  • skin diseases
  • cardiovascular disease
  • diagnosed or suspected hepatic or metabolic disease including diabetes
  • statin or other cholesterol-lowering medication
See the full eligibility criteria
Who can join
  • 18 - 24 years of age
  • no history of e-cigarette use (control) OR current with 6 months or more history of e-cigarette use (chronic use).
What rules you out
  • tobacco cigarette use (current or history of)
  • use of stimulant drugs
  • skin diseases
  • cardiovascular disease
  • diagnosed or suspected hepatic or metabolic disease including diabetes
  • statin or other cholesterol-lowering medication
  • antihypertensive medication
  • current pregnancy or breastfeeding
  • blood pressure greater than or equal to 140mmHg systolic and/or greater than or equal to 90mmHg diastolic
  • allergy to materials used during the experiment
  • known allergies to salsalate or other study drugs

The study team makes the final eligibility decision.

Where it's taking place

  • Iowa City, Iowa, United States

Questions & answers

Do participants get paid in this trial?

This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.

Is it free to join, and do I need insurance?

Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.

How long does this study last?

The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.

Who can join this trial?

This study is enrolling all sexes, 18 years to 24 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.

Where is this trial taking place?

Study sites include Iowa City, Iowa, United States. Enter your location above to see the nearest site and check your eligibility.

Explore other conditions

BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.