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New treatment option for Irritability
Official title Study Brain Mechanisms of Frustration With Magnetoencephalography in Healthy Volunteers
ClinicalTrials.gov ID: NCT06484088
What this study is testing
- What it's testing
- Background: Irritability can be defined as an unusually strong response to frustration; these responses may include severe temper outbursts and a constant grumpy mood. Irritability is a common symptom of many mental health disorders.
- Phase 1: an early, usually small safety study
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 55. Healthy volunteers may be eligible.
You may be able to join if
- This study will include adult healthy volunteers.
- Age: 18-55
- Consent: can give consent
- Speak and read English --The instruments have not been validated in other languages.
- At the NIH site, previously screened through other NIH protocols such as protocol 01-M-0254, 17-M-0181, and 93-M-0170 and determined eligible as...
You likely can't join if
- An individual who meets any of the following criteria will be excluded from participation in this study: -Any serious medical condition
- History, physical exam, or laboratory testing including drug abuse screen. -Prescription and over-the-counter medications and dietary supplements...
- History -Any current psychiatric diagnosis
- SCID-V, clinical assessment, or history. -Pregnancy
- Pregnancy testing will be done before all MRIs. -People who work on night shifts
- History -Drug use
See the full eligibility criteria
- This study will include adult healthy volunteers.
- Age: 18-55
- Consent: can give consent
- Speak and read English --The instruments have not been validated in other languages.
- At the NIH site, previously screened through other NIH protocols such as protocol 01-M-0254, 17-M-0181, and 93-M-0170 and determined eligible as healthy volunteers.
- An individual who meets any of the following criteria will be excluded from participation in this study: -Any serious medical condition
- History, physical exam, or laboratory testing including drug abuse screen. -Prescription and over-the-counter medications and dietary supplements with psychoactive properties (e.g., St. John's Wort, Melatonin, Valerian)...
- History -Any current psychiatric diagnosis
- SCID-V, clinical assessment, or history. -Pregnancy
- Pregnancy testing will be done before all MRIs. -People who work on night shifts
- History -Drug use
- people with drug use or positive drug screen more than two years ago are eligible for participation. -Need to wear eye glasses to work with computers\
- History -Need to wear contact lenses to work with computers\ \ ,\ \ \
- History -Dental retainer\ \
- people wearing removable dental retainers are eligible for participation
- Eye glasses create artifacts in MEG and their rigid shape does not fit well in the MEG scanner. The MEG core has plastic optometry lenses that can be placed in paper frames. However, the paper frames need to be secured...
- Only applies to the NIH site.
- Contact lenses create artifacts that interfere with eye-tracking.
The study team makes the final eligibility decision.
Where it's taking place
- Bethesda, Maryland, United States
- College Station, Texas, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 55 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Bethesda, Maryland, United States; College Station, Texas, United States. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.