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New treatment option for Overt Hepatic Encephalopathy
Official title Human Albumin Infusion in Liver Cirrhosis and Overt Hepatic Encephalopathy (HACHE)
ClinicalTrials.gov ID: NCT06483737
What this study is testing
What is Human albumin infusion at a modified dosage?
Human albumin infusion at a modified dosage is an investigational medicine, given as an infusion into a vein, being studied as a potential treatment for overt hepatic encephalopathy.
Also referred to as AlbuRx.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- Hepatic encephalopathy (HE), a severe complication of decompensated cirrhosis, is characterized as neurocognitive dysfunction. Emerging evidence suggests the potential role of human albumin infusion for the treatment of HE, but its optimal dosage remains undefined.
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- A definite diagnosis of liver cirrhosis and overt HE
- A serum albumin level of 23-30g/L
- Age ≥18 years old
- Sign the informed consent
You likely can't join if
- Contraindications to human albumin infusion
- A history of transjugular intrahepatic portosystemic shunt
- A diagnosis of acute liver failure
- Severe heart and/or lung diseases
- Psychiatric or nervous diseases
- Pregnant or lactating
The study team makes the final eligibility decision.
Where it's taking place
- Shenyang, Liaoning, China
Compensation & support
A stipend or compensation may be offered.
Compensation mentioned.
ClinicalTrials.gov doesn't provide a reliable structured field for payment or travel support - confirm details with the study team.
Questions & answers
Do participants get paid in this trial?
This study's listing includes signals that participants may be compensated or receive a stipend. Amounts vary and are set by the study team - confirm the details with them.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Shenyang, Liaoning, China. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.