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New treatment option for Nosocomial Infection
Official title Diagnostic of D-lactate in Cerebrospinal Fluid Level in Patients With Suspected Ventriculostomy-related Meningitis
ClinicalTrials.gov ID: NCT06482463
What this study is testing
What is CSF sample?
CSF sample is an investigational medicine, being studied as a potential treatment for nosocomial infection.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- The TOTEM study is a single-center study designed to evaluate the performance of the D-lactate assay in cerebrospinal fluid (CSF) for the diagnosis of ventriculostomy-related nosocomial meningitis. The study will be conducted in the neurosurgical intensive care unit of the Toulouse University Hospital, in patients with a suspected diagnosis of ventriculostomy-related nosocomial meningitis.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- Age ⩾ 18 years.
- Patient with an external ventriculostomy implanted at the Toulouse University Hospital.
- Patient suspected of nosocomial meningitis due to a febrile syndrome (in the absence of any other identified infectious site), headache, nausea...
- Patient having expressed oral consent, after free and informed information.
- Patient affiliated to a social security scheme.
You likely can't join if
- Diagnosis of community meningitis.
- Proven or suspected meningitis and/or ventriculitis during the previous month.
- Diagnosis of nosocomial meningitis made in another medical centre prior to admission.
- Short bowel syndrome.
- Acute mesenteric ischaemia.
- End-stage renal failure (GFR \< 15 ml/min/m2).
See the full eligibility criteria
- Age ⩾ 18 years.
- Patient with an external ventriculostomy implanted at the Toulouse University Hospital.
- Patient suspected of nosocomial meningitis due to a febrile syndrome (in the absence of any other identified infectious site), headache, nausea, lethargy, change in neurological status, meningeal syndrome, epileptic...
- Patient having expressed oral consent, after free and informed information.
- Patient affiliated to a social security scheme.
- Diagnosis of community meningitis.
- Proven or suspected meningitis and/or ventriculitis during the previous month.
- Diagnosis of nosocomial meningitis made in another medical centre prior to admission.
- Short bowel syndrome.
- Acute mesenteric ischaemia.
- End-stage renal failure (GFR \< 15 ml/min/m2).
- Peritoneal dialysis.
- Patient participating in another research protocol with an exclusion period still in progress.
- Pregnant or breastfeeding woman.
- Patient under guardianship or trusteeship, persons placed under the protection of justice
The study team makes the final eligibility decision.
Where it's taking place
- Toulouse, France
Compensation & support
Compensation mentioned.
ClinicalTrials.gov doesn't provide a reliable structured field for payment or travel support - confirm details with the study team.
Questions & answers
Do participants get paid in this trial?
This study's listing includes signals that participants may be compensated or receive a stipend. Amounts vary and are set by the study team - confirm the details with them.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Toulouse, France. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.