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New treatment option for Hyperthermia
Official title Predicting Responses to Exhausting, Prolonged, And Repeated Exercise Demands (PREPARED) for Heat
ClinicalTrials.gov ID: NCT06475339
What this study is testing
- What it's testing
- The overall goal of this project is to identify a work/rest cycle that allows for faster mission completion needed in emergency situations, compared to current Army heat guidance, while mitigating heat strain and neuromuscular fatigue. This project will determine the trade-off between faster mission completion and risk of heat strain and physical performance decrements.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 39. Healthy volunteers may be eligible.
You may be able to join if
- Healthy individuals
- Physically active
You likely can't join if
- History of cardiovascular, metabolic (such as clinical thyroid disease), respiratory, neural, or renal disease
- Hypertensive (systolic blood pressure \> 139 mmHg, diastolic blood pressure \> 89 mmHg) or tachycardic (heart rate \> 100 bpm) during the screening...
- Taking medications or supplements known to effect physiologic responses to exercise or thermoregulation (e.g., beta blockers, omega-3 fatty acids...
- Tobacco or nicotine use currently or in the past six months
- Musculoskeletal injury expected to impact exercise in the protocol
- A positive pregnancy test at any point in the study
See the full eligibility criteria
- Healthy individuals
- Physically active
- History of cardiovascular, metabolic (such as clinical thyroid disease), respiratory, neural, or renal disease
- Hypertensive (systolic blood pressure \> 139 mmHg, diastolic blood pressure \> 89 mmHg) or tachycardic (heart rate \> 100 bpm) during the screening visit
- Taking medications or supplements known to effect physiologic responses to exercise or thermoregulation (e.g., beta blockers, omega-3 fatty acids, statins, aspirin)
- Tobacco or nicotine use currently or in the past six months
- Musculoskeletal injury expected to impact exercise in the protocol
- A positive pregnancy test at any point in the study
- Study physician discretion based on any other medical condition or medication
- Inability to understand or follow instructions or the protocol
- Gastrointestinal disease or previous surgery prohibiting core temperature capsule use. Participants with a contraindication can opt to insert the pill rectally as a suppository.
The study team makes the final eligibility decision.
Where it's taking place
- Buffalo, New York, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 39 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Buffalo, New York, United States. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.