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Tests treatment safety and results for Allergic Rhinitis
Official title Efficacy and Safety of Arbidol in the Treatment of Allergic Rhinitis
ClinicalTrials.gov ID: NCT06462417
What this study is testing
What is Arbidol?
Arbidol is an investigational medicine, given as a pill taken by mouth, being studied as a potential treatment for allergic rhinitis.
Also referred to as Arbidol Hydrochloride.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- The most important treatment for AR is topical nasal medications (including nasal corticosteroids, nasal antihistamines, nasal decongestants, and nasal saline irrigation etc.), which are still limited. Arbidol may inhibit molecular targets involved in the pathogenesis of AR.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 65
You may be able to join if
- 1\. Patients with allergic rhinitis (in line with the diagnostic criteria of the "Guidelines for the Diagnosis and Treatment of Allergic Rhinitis...
- 2\. At least 2 nasal symptoms are moderate or above (referring to sneezing, runny nose, nasal itching, nasal congestion with at least 2 symptoms ≥2...
- 3\. Female people are not pregnant or lactating and have no pregnancy and lactation plans during the trial medication period.
- 4\. The subject has not participated in other clinical trials in the previous three months and agrees not to participate in other clinical trials...
- 5\. The subject/legally authorized representative understands the purpose and procedures of the trial and voluntarily signs the informed consent...
You likely can't join if
- 1\. Who are allergic to Arbidol.
- 2\. Patients with abnormal liver and kidney function (ALT and AST exceed the maximum limit of normal value by 1.5 times, and Cr exceeds the upper...
- 3\. Patients with abnormal ECG parameters and clinically significant (PR\>220ms, QRS\>120ms, QTc\>450ms) and bradycardia.
- 4\. Patients with severe asthma or acute asthma exacerbations.
- 5\. Patients with structural heart disease, severe hypertension (blood pressure greater than 180/110mmHg), diabetes, hyperthyroidism, malignant...
- 6\. Patients with nasal polyps, severe deviated nasal septum, sinusitis, and hypertrophic rhinitis.
See the full eligibility criteria
- 1\. Patients with allergic rhinitis (in line with the diagnostic criteria of the "Guidelines for the Diagnosis and Treatment of Allergic Rhinitis (2015, Tianjin)" formulated by the Rhinology Group of the...
- 2\. At least 2 nasal symptoms are moderate or above (referring to sneezing, runny nose, nasal itching, nasal congestion with at least 2 symptoms ≥2 points).
- 3\. Female people are not pregnant or lactating and have no pregnancy and lactation plans during the trial medication period.
- 4\. The subject has not participated in other clinical trials in the previous three months and agrees not to participate in other clinical trials before reaching the endpoint of this trial.
- 5\. The subject/legally authorized representative understands the purpose and procedures of the trial and voluntarily signs the informed consent form, voluntarily participates in the study and complies with the study...
- 1\. Who are allergic to Arbidol.
- 2\. Patients with abnormal liver and kidney function (ALT and AST exceed the maximum limit of normal value by 1.5 times, and Cr exceeds the upper limit of normal value).
- 3\. Patients with abnormal ECG parameters and clinically significant (PR\>220ms, QRS\>120ms, QTc\>450ms) and bradycardia.
- 4\. Patients with severe asthma or acute asthma exacerbations.
- 5\. Patients with structural heart disease, severe hypertension (blood pressure greater than 180/110mmHg), diabetes, hyperthyroidism, malignant tumors, immunocompromise, and mental illness. Patients with structural...
- 6\. Patients with nasal polyps, severe deviated nasal septum, sinusitis, and hypertrophic rhinitis.
- 7\. Who have participated in other clinical studies within 3 months.
- 8\. Women are pregnant or lactating, in childbearing age with positive blood pregnancy test, or have pregnancy and lactation plans during the trial medication.
- 9\. Drug abuse and alcoholism.
- 10\. Who have received allergen-specific immunotherapy within 3 years.
- 11\. Positive infectious disease screening (hepatitis B surface antigen, hepatitis C antibody, AIDS antibody and treponema pallidum antibody).
- 12\. Who should not be included if there are other reasons in the opinion of the investigator.
The study team makes the final eligibility decision.
Where it's taking place
- Wuhan, Hubei, China
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 65 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Wuhan, Hubei, China. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.