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New treatment option for Metformin
Official title Pilot Study on Evaluating the Geroprotective Effect of Metformin
ClinicalTrials.gov ID: NCT06459310
What this study is testing
What is Metformin Hydrochloride tablet?
Metformin Hydrochloride tablet is an investigational medicine, given as an once-daily pill taken by mouth, being studied as a potential treatment for metformin.
Also referred to as Metformin.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- The objective of this research is to assess the efficacy of oral metformin in mitigating the aging process in middle-aged and elderly males, to pinpoint sensitive indicators of human senescence, and to offer innovative frameworks and scientific insights for pharmaceutical interventions in aging.
- Phase 2: a mid-size study of how well it works
- You might receive a placebo (an inactive treatment) instead of the study drug.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 65, men only. Healthy volunteers may be eligible.
You may be able to join if
- Male
- Age 55-65; 18-28;
- Able to understand and execute instructions;
- After reading the consent form, be able to answer questions about the study and demonstrate understanding of the protocol;
- Be able to participate in regular follow-up visits.
You likely can't join if
- Severe chronic or acute disease: cancer, clinically significant congestive heart failure, chronic obstructive pulmonary disease (COPD), previous or...
- BMI\ 30;
- Persistent alcohol or drug abuse;
- Treatment with drugs known to affect glucose metabolism (other diabetes drugs, systemic glucocorticoids, niacin);
- Hypersensitivity to metformin or any component of the preparation;
- Have taken metformin, low-dose aspirin, acarbose, vitamin C in the recent (3 months);
See the full eligibility criteria
- Male
- Age 55-65; 18-28;
- Able to understand and execute instructions;
- After reading the consent form, be able to answer questions about the study and demonstrate understanding of the protocol;
- Be able to participate in regular follow-up visits.
- Severe chronic or acute disease: cancer, clinically significant congestive heart failure, chronic obstructive pulmonary disease (COPD), previous or new-onset diabetes, inflammatory state, serum creatinine \>1.5 mg/dl...
- BMI\ 30;
- Persistent alcohol or drug abuse;
- Treatment with drugs known to affect glucose metabolism (other diabetes drugs, systemic glucocorticoids, niacin);
- Hypersensitivity to metformin or any component of the preparation;
- Have taken metformin, low-dose aspirin, acarbose, vitamin C in the recent (3 months);
- Unable to provide informed consent;
- Other circumstances in which the researcher believes that the physical factors of the participants may adversely affect the research process or results.
The study team makes the final eligibility decision.
Where it's taking place
- Beijing, China
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling male, 18 years to 65 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Beijing, China. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.