BridgeMD
New treatment option for Pharmacogenomic Drug Interaction
Official title Trial of Precision Medicine in Emergency Departments
ClinicalTrials.gov ID: NCT06448091
What this study is testing
- What it's testing
- The objectives of this study are to (1) test the feasibility of the clinical implementation of preemptive pharmacogenetic (PGx) testing in the emergency department (ED) and (2) determine if PGx testing (with appropriate decision support) decreases ED return visits and hospitalizations. We will conduct a randomized, controlled, pragmatic clinical trial assessing both the real-world effectiveness as well as implementation outcomes using a targeted PGx testing panel in several UF Health EDs.
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 40 and older. Healthy volunteers may be eligible.
You may be able to join if
- Adults 40 years or older presenting to a participating ED
- Receipt of a new order/prescription for a selected PGx medication (Appendix 1), with a duration greater than 7 days, during the current ED visit or...
- Documentation of at least 2 prior ED or urgent care visits within the past 12 months
You likely can't join if
- Prior clinical pharmacogenetic test results within the EHR for genes relevant for this study (Appendix 1).
- History of hepatic or renal transplant
- History of severe liver disease (stage Child-Pugh C) or renal disease eGFR \<15 ml/min.
- Any medical condition that would prohibit the ability to complete the study
- Prisoners, wards of the state, or patients being held under the Baker Act or Marchman Act
- Life expectancy less than 6 months
The study team makes the final eligibility decision.
Where it's taking place
- Gainesville, Florida, United States
- Jacksonville, Florida, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 40 years and older. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Gainesville, Florida, United States; Jacksonville, Florida, United States. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.