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New treatment option for Acute Kidney Injury
Official title LoW Dose-Intensity vs. Standard Dose-Intensity COntinuous Renal ReplaceMent Therapy in Critically Ill Patients (WISDOM)
ClinicalTrials.gov ID: NCT06446739
What this study is testing
- What it's testing
- An estimated 10-15% of critically ill patients with acute kidney failure in the intensive care unit receive acute dialysis therapy. The majority of these patients initially receive a continuous form of dialysis therapy call continuous renal replacement therapy (CRRT).
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- age ≥ 18 years
- weight ≥ 55 kg
- plan to initiate CRRT or within 24 hours of having started CRRT for AKI
- expected to survive and receive CRRT for a duration of ≥ 48 hours
- able to provide informed consent or have an authorized representative provide consent after being informed on the details and risks of the trial...
You likely can't join if
- indication for sustained higher dose-intensity CRRT as designated by the attending clinicians
- end-stage kidney disease receiving maintenance dialysis
- receipt of any RRT for AKI during the current hospitalization
- inability to comply with the requirements of the study protocol.
The study team makes the final eligibility decision.
Where it's taking place
- Rochester, Minnesota, United States
- Calgary, Alberta, Canada
- Edmonton, Alberta, Canada
- St. Albert, Alberta, Canada
- Hamilton, Ontario, Canada
- North York, Ontario, Canada
- Toronto, Ontario, Canada
- Regina, Saskatchewan, Canada
- London, United Kingdom
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Rochester, Minnesota, United States; Calgary, Alberta, Canada; Edmonton, Alberta, Canada; St. Albert, Alberta, Canada; Hamilton, Ontario, Canada; North York, Ontario, Canada and 3 more location(s). Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.