BridgeMD
New treatment option for Alzheimer Disease
Official title Paper-Based and Smartphone-Based Memory Supports
ClinicalTrials.gov ID: NCT06444841
What this study is testing
- What it's testing
- Alzheimer's disease and related dementias lead to marked declines in daily functioning, independence, and quality of life. One of the earliest cognitive changes in these conditions is impairment in prospective memory, or the ability to remember future intentions such as taking medications at a given time.
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 50 and older
You may be able to join if
- Demonstrate capacity to consent via structured interview that involves reviewing core study features and probing for understanding of potential...
- Clinical features consistent with a diagnosis of MCI or dementia. For clinic-referred participants, available records will be reviewed to ensure the...
- Cognitive status for inclusion will be assessed by Montreal Cognitive Assessment (MoCA) scores of 17-25 (or 12-18 for the telephone version if...
- Functional status will be assessed via semi-structured interview with the Global Deterioration Scale (GDS), with stage 3 or 4 indicating independence...
- Adequate sensory and motor abilities to utilize a smartphone with accommodation.
You likely can't join if
- History of serious mental illness including schizophrenia or bipolar disorder that is judged by the clinician to be the primary cause of cognitive...
- Indication of moderate or severe dementia based on clinical documentation, MoCA score, and/or collateral/informant activities of daily living measure...
- Language difficulties significant enough to interfere with the screening procedures.
- Uncorrected hearing loss, vision loss, or motor dysfunction significant enough to interfere with training.
- No study partner.
- At the current time, individuals who do not identify as conversational in English will be excluded from participation. Co-Participant Exclusion...
See the full eligibility criteria
- Demonstrate capacity to consent via structured interview that involves reviewing core study features and probing for understanding of potential benefits/consequences of participating, and understanding that one can...
- Clinical features consistent with a diagnosis of MCI or dementia. For clinic-referred participants, available records will be reviewed to ensure the clinical diagnosis meets published diagnostic guidelines. If there is...
- Cognitive status for inclusion will be assessed by Montreal Cognitive Assessment (MoCA) scores of 17-25 (or 12-18 for the telephone version if in-clinic assessment is not feasible). While some studies suggested that...
- Functional status will be assessed via semi-structured interview with the Global Deterioration Scale (GDS), with stage 3 or 4 indicating independence in basic self-maintenance activities.
- Adequate sensory and motor abilities to utilize a smartphone with accommodation.
- Availability of a co-participant who sees the participant at least once a month. Co-Participant
- The co-participant will need to be over the age of 18, consent to participation, and see the participant at least once per month.
- History of serious mental illness including schizophrenia or bipolar disorder that is judged by the clinician to be the primary cause of cognitive decline.
- Indication of moderate or severe dementia based on clinical documentation, MoCA score, and/or collateral/informant activities of daily living measure during the screening process (GDS score ≥5).
- Language difficulties significant enough to interfere with the screening procedures.
- Uncorrected hearing loss, vision loss, or motor dysfunction significant enough to interfere with training.
- No study partner.
- At the current time, individuals who do not identify as conversational in English will be excluded from participation. Co-Participant Exclusion Criteria:
- Sees participant less than once per month.
- At the current time, individuals who do not identify as conversational in English will be excluded from participation.
The study team makes the final eligibility decision.
Where it's taking place
- Austin, Texas, United States
- Temple, Texas, United States
- Waco, Texas, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 50 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Austin, Texas, United States; Temple, Texas, United States; Waco, Texas, United States. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.