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New treatment option for Bronchiectasis Adult
Official title Benefits of Inhalation of Hypertonic Saline Solution Prior to Physiotherapy ELTGOL Technique in Bronchiectasis
ClinicalTrials.gov ID: NCT06443658
What this study is testing
What is Isotonic saline?
Isotonic saline is an investigational medicine, given as an once-daily inhaled treatment, being studied as a potential treatment for bronchiectasis adult.
Also referred to as Physiologic saline.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- Bronchiectasis is a chronic bronchial disease in which the usual capacity to remove secretions does not function correctly, causing mucus retention that leads to chronic infection. As with all infections, the use of antibiotics and puss removal are essential treatment elements.
- Phase 3: a large, late-stage study
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- Adult patients with bronchiectasis confirmed by high resolution computed tomography
- No exacerbations in the previous month
- Chronic mucopurulent and purulent sputum
- ≥10ml daily expectoration
- At least one exacerbation in the previous year
You likely can't join if
- Current smokers or a smoking history of ≥20 p-y
- Asthma, allergic bronchopulmonary aspergillosis or Cystic Fibrosis
- Pregnant or lactating women
- Following mucoactive treatment in the previous month
- Inability to perform ELTGOL, spirometry or to attend visits
- Practicing pulmonary rehabilitation in the previous 6 months
See the full eligibility criteria
- Adult patients with bronchiectasis confirmed by high resolution computed tomography
- No exacerbations in the previous month
- Chronic mucopurulent and purulent sputum
- ≥10ml daily expectoration
- At least one exacerbation in the previous year
- (Forced expiratory volume the 1st second) FEV1 ≥30% after bronchodilation
- Sign the informed consent
- Current smokers or a smoking history of ≥20 p-y
- Asthma, allergic bronchopulmonary aspergillosis or Cystic Fibrosis
- Pregnant or lactating women
- Following mucoactive treatment in the previous month
- Inability to perform ELTGOL, spirometry or to attend visits
- Practicing pulmonary rehabilitation in the previous 6 months
- Change of treatment the previous month
- Uncontrolled hypertension
The study team makes the final eligibility decision.
Where it's taking place
- Girona, Spain
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Girona, Spain. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.