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New treatment option for Infections, Bacterial
Official title Therapeutic Options for CRAB
ClinicalTrials.gov ID: NCT06440304
What this study is testing
What is Fosfomycin?
Fosfomycin is an investigational medicine, given as an once-daily infusion into a vein, being studied as a potential treatment for infections, bacterial.
Also referred to as Fosfomycin with Colistin.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- CRAB infections in ICUs are on the rise, leading to higher morbidity, mortality, and healthcare costs due to resistance to most antibiotics, including carbapenems. The main resistance mechanisms include carbapenemases, efflux pumps, and changes in the bacterial cell wall.
- Phase 4: studies an already-approved treatment
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 90
You may be able to join if
- Surgical patients (abdominal, vascular, and polytraumatized patients)
- Older than 18 years
- Require postoperative treatment in the ICU
- A positive sample (surveillance or diagnostic) for A. baumannii with signs of systemic infection Infection will be defined as a diagnostic...
You likely can't join if
- Allergy to the study medications
- Positive surveillance swabs for A. baumannii without signs of systemic infection
- Positive findings (surveillance or diagnostic) for carbapenem-sensitive A. baumannii
- Refusal to participate in the research
The study team makes the final eligibility decision.
Where it's taking place
- Zagreb, Croatia
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 90 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Zagreb, Croatia. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.