BridgeMD
New treatment option for Opioid Use Disorder
Official title tDCS to Decrease Opioid Relapse (UH3)
ClinicalTrials.gov ID: NCT06432465
What this study is testing
- What it's testing
- Investigators will measure behavioral and brain responses following transcranial direct current stimulation (tDCS) to the dorsolateral prefrontal cortex (DLPFC) (anode on right DLPFC, cathode on the left DLPFC) delivered during cognitive control network (CCN) priming. In Phase I, the EEG provided validation of expected changes in these networks following tDCS stimulation of the DLPFC.
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 21 to 60
You may be able to join if
- current opioid dependence
- between 21-60 years of age
- recent initiation of buprenorphine or methadone (≤90 days)
- enrolled in Butler Hospital's Alcohol and Drug Inpatient Unit, Alcohol and Drug Partial Hospital Treatment Program, Intensive Outpatient Services, or...
You likely can't join if
- current diagnosis of organic brain disorder (e.g., Parkinson's disease, Huntington's disease, multiple sclerosis, intracranial mass/infection...
- bipolar, schizophrenia, schizoaffective, or schizophreniform disorder, or current psychosis associated with any disorder
- current suicidality
- evidence of significant neurocognitive dysfunction
- conditions associated with heightened tDCS risks, e.g., seizure disorder, nonremovable intracranial metal objects (other than dental fillings and...
- probation/parole requirements or an upcoming move that might interfere with protocol participation
See the full eligibility criteria
- current opioid dependence
- between 21-60 years of age
- recent initiation of buprenorphine or methadone (≤90 days)
- enrolled in Butler Hospital's Alcohol and Drug Inpatient Unit, Alcohol and Drug Partial Hospital Treatment Program, Intensive Outpatient Services, or Outpatient Services at Butler Hospital OR receive opioid-treatment...
- current diagnosis of organic brain disorder (e.g., Parkinson's disease, Huntington's disease, multiple sclerosis, intracranial mass/infection, hydrocephalus)
- bipolar, schizophrenia, schizoaffective, or schizophreniform disorder, or current psychosis associated with any disorder
- current suicidality
- evidence of significant neurocognitive dysfunction
- conditions associated with heightened tDCS risks, e.g., seizure disorder, nonremovable intracranial metal objects (other than dental fillings and dental implants), skin disease or active lesions on the scalp...
- probation/parole requirements or an upcoming move that might interfere with protocol participation
- planning to terminate buprenorphine or methadone in less than 3 months
- current pregnancy or plan to become pregnant in the next month.
The study team makes the final eligibility decision.
Where it's taking place
- Providence, Rhode Island, United States
Compensation & support
Compensation mentioned.
ClinicalTrials.gov doesn't provide a reliable structured field for payment or travel support - confirm details with the study team.
Questions & answers
Do participants get paid in this trial?
This study's listing includes signals that participants may be compensated or receive a stipend. Amounts vary and are set by the study team - confirm the details with them.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 21 years to 60 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Providence, Rhode Island, United States. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.