Recruiting PHASE2 Esophageal Cancer

New treatment option for Esophageal Cancer

Official title Nimotuzumab Concurrent With Chemoradiotherapy for Esophageal Cancer Patients

ClinicalTrials.gov ID: NCT06429839

What this study is testing

What is Nimotuzumab with chemoradiotherapy?

Nimotuzumab with chemoradiotherapy is an investigational medicine, given as an once-daily pill taken by mouth, being studied as a potential treatment for esophageal cancer.

Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.

What it's testing
Elderly or malnourished patients diagnosed with locally advanced esophageal squamous cell carcinoma (ESCC) had poor prognosis. Radiotherpy was an important and effective treatment in treating ESCC.
  • Phase 2: a mid-size study of how well it works

A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.

Who can take part

Ages 18 to 80

You may be able to join if

  • Histologically confirmed esophageal squamous cell carcinoma.
  • No previous treatment for the esophageal carcinoma.
  • KPS score ≥70.
  • NRS-2002 score≥2.
  • Main organs and bone marrow function are normal: routine blood tests: hemoglobin (Hb) ≥100g/L ; absolute neutrophil count (NEUT)≥1.5×109/L; platelets...

You likely can't join if

  • Previous treatment of the esophageal cancer with surgery, radiation, or chemotherapy.
  • Those combined with other primary malignant tumors other than esophageal cancer (except cured basal cell carcinoma of the skin and carcinoma in situ...
  • At the time of diagnosis, there were distant and hematogenous metastases beyond the supraclavicular lymph node region, including retroperitoneal...
  • There are active infections, such as active tuberculosis and hepatitis
  • There are contraindications to targeted therapy.

The study team makes the final eligibility decision.

Where it's taking place

  • Beijing, China

Questions & answers

Do participants get paid in this trial?

This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.

Is it free to join, and do I need insurance?

Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.

How long does this study last?

The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.

Who can join this trial?

This study is enrolling all sexes, 18 years to 80 years. The study team makes the final eligibility decision.

Where is this trial taking place?

Study sites include Beijing, China. Enter your location above to see the nearest site and check your eligibility.

Explore other conditions

BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.