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New treatment option for Migraine Disorders
Official title The Role of Cytokines and Regulatory T Lymphocytes in Migraine Pathophysiology.
ClinicalTrials.gov ID: NCT06426316
What this study is testing
What is Blood test?
Blood test is an investigational medicine, given as an infusion into a vein, being studied as a potential treatment for migraine disorders.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- Migraine is a frequent and debilitating neurologic disorder. It is more frequent in women, and more prevalent in patients with autoimmune and/or inflammatory diseases such as multiple sclerosis (MS), rheumatoid arthritis (RA), Crohn's disease (CD), systemic lupus erythematosus (SLE) and endometriosis, whereas patients with long standing type 1 diabetes mellitus (T1DM) - an autoimmune but non inflammatory disease - seem to be less affected compared to the general population.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 50, women only. Healthy volunteers may be eligible.
You may be able to join if
- female
- 18 - 50 years of age
- at least 50 kg
- autoimmune/inflammatory disease groups : with a diagnosis of multiple sclerosis, systemic lupus erythematous, rheumatoid arthritis, Crohn's disease...
- migraine group : with a diagnosis of migraine with at least 4 headache days per month
You likely can't join if
- BMI \ or = 30kg/m²
- type 2 diabetes, immune deficit, other chronic autoimmune or inflammatory disease
- non-migraine headache, except for tension type headache of less than 4 days/month
- pregnancy, delivery, miscarriage, breast-feeding, participation in a medically assisted human reproduction program (ovary stimulation/hormone...
- Menopause, hysterectomy, or bilateral oophorectomy
- Hormone therapy (besides contraception and treatment of endometriosis)
See the full eligibility criteria
- female
- 18 - 50 years of age
- at least 50 kg
- autoimmune/inflammatory disease groups : with a diagnosis of multiple sclerosis, systemic lupus erythematous, rheumatoid arthritis, Crohn's disease, type 1 diabetes or endometriosis
- migraine group : with a diagnosis of migraine with at least 4 headache days per month
- BMI \ or = 30kg/m²
- type 2 diabetes, immune deficit, other chronic autoimmune or inflammatory disease
- non-migraine headache, except for tension type headache of less than 4 days/month
- pregnancy, delivery, miscarriage, breast-feeding, participation in a medically assisted human reproduction program (ovary stimulation/hormone therapy) \< 3 months before blood sampling
- Menopause, hysterectomy, or bilateral oophorectomy
- Hormone therapy (besides contraception and treatment of endometriosis)
- bone marrow or solid organ transplant
- guardianship, curatorship, safeguard of justice or deprivation of liberty
- for patients : diagnosis of several autoimmune or inflammatory diseases
- for controls : diagnosis of an autoimmune or inflammatory disease
- for non-migraine participants : migraine
The study team makes the final eligibility decision.
Where it's taking place
- Clermont-Ferrand, AURA, France
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling female, 18 years to 50 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Clermont-Ferrand, AURA, France. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.