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New treatment option for Healthy Aging
Official title Nicotinamide Riboside Supplementation and Exercise Training to Promote Healthy Longevity
ClinicalTrials.gov ID: NCT06425042
What this study is testing
- What it's testing
- The prevalence of age-related chronic diseases (like obesity, type 2 diabetes and cardiovascular diseases) is mounting worldwide, reaching pandemic proportions. These age-related chronic diseases are associated with diminished skeletal muscle mitochondrial function in humans.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 60 to 80. Healthy volunteers may be eligible.
You may be able to join if
- Participants are able to provide signed and dated written informed consent prior to any study specific procedures
- Aged ≥ 60 and ≤ 80 years
- Body mass index (BMI) 25 - 35 kg/m2
- Stable dietary habits (no weight loss or gain \> 5 kg in the past 3 months)
- No signs of active cardiovascular disease, liver or kidney malfunction
You likely can't join if
- Patients with congestive heart failure and and/or severe renal and or liver insufficiency
- Uncontrolled hypertension
- Any contra-indication for MRI scanning
- Alcohol consumption of \> 3 servings per day for man and \>2 servings per day for woman
- Smoking
- Unstable body weight (weight gain or loss \> 5kg in the last 3 months)
See the full eligibility criteria
- Participants are able to provide signed and dated written informed consent prior to any study specific procedures
- Aged ≥ 60 and ≤ 80 years
- Body mass index (BMI) 25 - 35 kg/m2
- Stable dietary habits (no weight loss or gain \> 5 kg in the past 3 months)
- No signs of active cardiovascular disease, liver or kidney malfunction
- Patients with congestive heart failure and and/or severe renal and or liver insufficiency
- Uncontrolled hypertension
- Any contra-indication for MRI scanning
- Alcohol consumption of \> 3 servings per day for man and \>2 servings per day for woman
- Smoking
- Unstable body weight (weight gain or loss \> 5kg in the last 3 months)
- Engagement in structured exercise activities \> 2 hours a week
- Previous enrolment in a clinical study with an investigational product during the last 3 months or as judged by the Investigator which would possibly hamper our study results
- Use of food supplements containing NR or Resveratrol (similar working mechanisms)
The study team makes the final eligibility decision.
Where it's taking place
- Santiago, Santiago Metropolitan, Chile
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 60 years to 80 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Santiago, Santiago Metropolitan, Chile. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.