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New treatment option for Endocarditis, Infective
Official title Ampicillin and Ceftriaxone for the Treatment of Enterococcus Faecalis Infective Endocarditis.
ClinicalTrials.gov ID: NCT06423898
What this study is testing
What is Ampicillin plus ceftriaxone in continuous infusion?
Ampicillin plus ceftriaxone in continuous infusion is an investigational medicine, given as an infusion into a vein, being studied as a potential treatment for endocarditis, infective.
Also referred to as Experimental regimen.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- Phase IV, open-label, randomized and multicenter clinical trial to prove that patients with Enterococcus faecalis infective endocarditis treated with an antibiotic treatment as a continuous infusion is non-inferior to the standard treatment, usually administered in hospitalized patients.
- Phase 4: studies an already-approved treatment
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- Adult patients
- Possible or definitive diagnosis of infective endocarditis due to Enterococcus faecalis
- Signed informed consent of patients
You likely can't join if
- Allergy to penicillins or cephalosporins
- Pregnancy and lactation
- Polymicrobial infection including microorganisms different to E. faecalis
The study team makes the final eligibility decision.
Where it's taking place
- Alava, Spain
- Barakaldo, Spain
- Barcelona, Spain
- Donostia / San Sebastian, Spain
- Granada, Spain
- Logroño, Spain
- Madrid, Spain
- Málaga, Spain
- San Cristóbal de La Laguna, Spain
- Santander, Spain
- Seville, Spain
- Terrassa, Spain
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Alava, Spain; Barakaldo, Spain; Barcelona, Spain; Donostia / San Sebastian, Spain; Granada, Spain; Logroño, Spain and 6 more location(s). Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.