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New treatment option for Analgesics, Opioid
Official title Opioid-free Anesthesia as an Alternative to General Anesthesia in Abdominal Surgery
ClinicalTrials.gov ID: NCT06380244
What this study is testing
- What it's testing
- Opioid-free anesthesia (OFA) is a multimodal technique that eliminates intraoperative opioids by combining dexmedetomidine, ketamine, lidocaine, NSAIDs, and regional analgesia. Growing evidence suggests OFA reduces postoperative opioid consumption, opioid-related adverse effects, and may have favorable oncological implications in cancer surgery.
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 75
You may be able to join if
- Adults aged 18-75 years scheduled for elective urological surgery under general anesthesia: laparoscopic or robotic nephrectomy, laparoscopic or...
- Ability to operate a patient-controlled analgesia (PCA) pump postoperatively.
- Ability to understand and use the Numeric Rating Scale (NRS) for pain assessment.
- Written informed consent.
You likely can't join if
- Patient's refusal to participate.
- Inability to operate the PCA pump.
- Inability to understand the NRS pain scale.
- Known hypersensitivity to any of the study drugs (anesthetics, ketamine, dexmedetomidine, ropivacaine, oxycodone, metamizole, paracetamol, ibuprofen).
- Second- or third-degree atrioventricular block, or symptomatic bradycardia.
- Chronic opioid use.
See the full eligibility criteria
- Adults aged 18-75 years scheduled for elective urological surgery under general anesthesia: laparoscopic or robotic nephrectomy, laparoscopic or robotic prostatectomy, or laparoscopic or robotic cystectomy.
- Ability to operate a patient-controlled analgesia (PCA) pump postoperatively.
- Ability to understand and use the Numeric Rating Scale (NRS) for pain assessment.
- Written informed consent.
- Patient's refusal to participate.
- Inability to operate the PCA pump.
- Inability to understand the NRS pain scale.
- Known hypersensitivity to any of the study drugs (anesthetics, ketamine, dexmedetomidine, ropivacaine, oxycodone, metamizole, paracetamol, ibuprofen).
- Second- or third-degree atrioventricular block, or symptomatic bradycardia.
- Chronic opioid use.
- Contraindication to the planned regional anesthesia technique (e.g. coagulopathy or therapeutic anticoagulation, infection at the puncture site).
The study team makes the final eligibility decision.
Where it's taking place
- Krakow, Lesser Poland Voivodeship, Poland
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 75 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Krakow, Lesser Poland Voivodeship, Poland. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.