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New treatment option for Chronic Obstructive Pulmonary Disease (COPD)
Official title Multi-Center Clean Air Randomized Controlled Trial in COPD
ClinicalTrials.gov ID: NCT06376994
What this study is testing
- What it's testing
- This is a multi-center randomized, sham-controlled clinical trial to determine the effectiveness of an air cleaner intervention aimed at improving indoor air quality on reducing COPD exacerbation risk and improving quality of life, functional status, rescue medication use.
- Phase 3: a large, late-stage study
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 40 and older
You may be able to join if
- To be eligible, people must meet all these criteria:
- Age ≥ 40 years.
- Self-report of physician diagnosis of COPD.
- Spirometry confirmed airway obstruction (post-bronchodilator spirometry of forced expiratory volume in 1 second (FEV1)/forced vital capacity (FVC) \<...
- Tobacco exposure ≥ 10 pack-years. This refers to regular cigarette tobacco consumption.
You likely can't join if
- To be eligible, people must not meet any one of these criteria:
- Living in a location other than home (e.g., long-term care facility, nursing home)
- Other chronic lung diseases, except asthma
- Condition with less than a year of life expectancy (e.g., metastatic cancer) or in hospice
- Spends \>2 months per year in location other than home; or plans to change residence in the next 12 months
- Pregnant or breastfeeding
See the full eligibility criteria
- To be eligible, people must meet all these criteria:
- Age ≥ 40 years.
- Self-report of physician diagnosis of COPD.
- Spirometry confirmed airway obstruction (post-bronchodilator spirometry of forced expiratory volume in 1 second (FEV1)/forced vital capacity (FVC) \< 0.7) as defined by the Global Initiative for Obstructive Lung Disease...
- Tobacco exposure ≥ 10 pack-years. This refers to regular cigarette tobacco consumption.
- Self-reported former smoker of at least 6 months' duration. This does not include e-cigarette use.
- COPD Assessment Test (CAT) score ≥ 10, Modified Medical Research Council dyspnea scale (mMRC) ≥ 2, or history of moderate or severe exacerbation in the past 12 months (as defined by history of receiving a course of...
- To be eligible, people must not meet any one of these criteria:
- Living in a location other than home (e.g., long-term care facility, nursing home)
- Other chronic lung diseases, except asthma
- Condition with less than a year of life expectancy (e.g., metastatic cancer) or in hospice
- Spends \>2 months per year in location other than home; or plans to change residence in the next 12 months
- Pregnant or breastfeeding
- Current air cleaner use in the home (\ If the individual is willing to discontinue use of the personal air cleaner, this person can be eligible if all other eligibility has been met)
- Inability to bring air cleaners (about 15 pounds each) into home, either by self, friend, or relative
- Deemed by the study investigator to be unable to complete study protocol, including likely lack of internet connectivity
- Participating in another treatment clinical trial
The study team makes the final eligibility decision.
Where it's taking place
- Birmingham, Alabama, United States
- Los Angeles, California, United States
- Iowa City, Iowa, United States
- Baltimore, Maryland, United States
- Salisbury, Maryland, United States
- Boston, Massachusetts, United States
- Ann Arbor, Michigan, United States
- Lebanon, New Hampshire, United States
- Cleveland, Ohio, United States
- West Reading, Pennsylvania, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 40 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Birmingham, Alabama, United States; Los Angeles, California, United States; Iowa City, Iowa, United States; Baltimore, Maryland, United States; Salisbury, Maryland, United States; Boston, Massachusetts, United States and 4 more location(s). Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.