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Compares treatment options for Dental Caries in Children
Official title Comparative Evaluation of Melatonin Versus MTA on Vital Pulp Therapy in Young Permanent First Molars: An in Vivo Study
ClinicalTrials.gov ID: NCT06372561
What this study is testing
What is Mineral trioxide aggregate (dressing material)?
Mineral trioxide aggregate (dressing material) is an investigational medicine, given as a pill taken by mouth, being studied as a potential treatment for dental caries in children.
Also referred to as MTA.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- The process of dental caries is dynamic and can be either reversible or irreversible depending on the balance between protective and pathologic factors in the oral cavity. Untreated dental caries causes pulpal injury, inflammation, and necrosis.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 6 to 8. Healthy volunteers may be eligible.
You may be able to join if
- 1- Apparently healthy and medically free children. 2- Their age ranges from 6-8 years. 3- Both boys and girls will be included. 4- Children should...
- No history of spontaneous pain, history of night pain or pain that not relieved by analgesics.
- No pain on percussion.
- No mobility.
- Absence of abscess, purulent sinus or soft tissue edema.
You likely can't join if
- Internal root resorption.
- External root resorption.
- Inter radicular or periapical bone destruction (radiolucency)
- A deep carious lesion radiologically that approaches the pulp
See the full eligibility criteria
- 1- Apparently healthy and medically free children. 2- Their age ranges from 6-8 years. 3- Both boys and girls will be included. 4- Children should have mandibular permanent first molars with the following clinical and...
- No history of spontaneous pain, history of night pain or pain that not relieved by analgesics.
- No pain on percussion.
- No mobility.
- Absence of abscess, purulent sinus or soft tissue edema.
- Bleeding should stop within 5 minutes after the amputated pulp stumps.
- Internal root resorption.
- External root resorption.
- Inter radicular or periapical bone destruction (radiolucency)
- A deep carious lesion radiologically that approaches the pulp
The study team makes the final eligibility decision.
Where it's taking place
- Ismailia, Egypt
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 6 years to 8 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Ismailia, Egypt. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.