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New treatment option for Aseptic Muscle Injury
Official title Effects of Protein and NAC Co-ingestion on Skeletal Muscle Recovery
ClinicalTrials.gov ID: NCT06367413
What this study is testing
- What it's testing
- Previous evidence suggests that though N-acetylcysteine (NAC) supplementation following eccentric exercise-induced muscle damage disrupts the skeletal muscle's repair and remodelling process at 8 days of recovery, it attenuates substantially the decline of skeletal muscle performance during the first 48 hours of recovery. The enhanced performance capacity during the first phase of recovery in response to NAC supplementation might be attributed to the altered redox status in skeletal muscle as a consequence of the NAC-mediated elevation of reduced glutathione (GSH) levels.
- You might receive a placebo (an inactive treatment) instead of the study drug, decided by chance. You may not know which one you got.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 27, men only. Healthy volunteers may be eligible.
You may be able to join if
- Free of asthma, kidney disease, bleeding disorders, peptic ulcers.
- Free of musculoskeletal injuries and limitations.
- Abstain from dietary energy restriction.
- Do not use medication such as anti-inflammatory drugs, antibiotics, antihypertensive drugs or anticoagulants.
- Do not use dietary supplements such as protein, carbohydrate, antioxidants, vitamins etc.
You likely can't join if
- Presence of asthma, kidney disease, bleeding disorders, peptic ulcers.
- Musculoskeletal injuries and limitations.
- Dietary energy restriction.
- Use of anti-inflammatory drugs, antibiotics, antihypertensive drugs or anticoagulants.
- Use of dietary supplements such as protein, carbohydrate, antioxidants, vitamins etc.
- N-acetylcysteine intolerance.
See the full eligibility criteria
- Free of asthma, kidney disease, bleeding disorders, peptic ulcers.
- Free of musculoskeletal injuries and limitations.
- Abstain from dietary energy restriction.
- Do not use medication such as anti-inflammatory drugs, antibiotics, antihypertensive drugs or anticoagulants.
- Do not use dietary supplements such as protein, carbohydrate, antioxidants, vitamins etc.
- Free of N-acetylcysteine intolerance.
- Non-smokers.
- Abstain from alcohol throughout the study.
- Presence of asthma, kidney disease, bleeding disorders, peptic ulcers.
- Musculoskeletal injuries and limitations.
- Dietary energy restriction.
- Use of anti-inflammatory drugs, antibiotics, antihypertensive drugs or anticoagulants.
- Use of dietary supplements such as protein, carbohydrate, antioxidants, vitamins etc.
- N-acetylcysteine intolerance.
- Smoking.
- Alcohol consumption during the study.
The study team makes the final eligibility decision.
Where it's taking place
- Trikala, Karies, Greece
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling male, 18 years to 27 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Trikala, Karies, Greece. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.