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New treatment option for Muscular Dystrophy, Duchenne
Official title The Effect of a Muscle-mimicking, Fabric-type Shoulder Orthosis on Functional Movements of the Upper Limb in Patients With Neuromuscular Disorder
ClinicalTrials.gov ID: NCT06363357
What this study is testing
- What it's testing
- The goal of this clinical trial is to investigate the effect of a muscle-mimicking, fabric-type shoulder orthosis on functional movements of the upper limb in patients with neuromuscular disorder. The main questions it aims to answer are: What is the impact of the muscle-mimicking, fabric-type shoulder orthosis on upper limb functional movements in patients with neuromuscular disorder?
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 10 and older
You may be able to join if
- Patients with a confirmed diagnosis of a neuromuscular disease (NMD) by genetic testing, muscle biopsy, or electrodiagnostic studies, presenting with...
- Muscular Dystrophies: Duchenne/Becker Muscular Dystrophy (DMD/BMD), Limb-Girdle Muscular Dystrophy (LGMD), Facioscapulohumeral Muscular Dystrophy...
- Motor Neuron Diseases: Spinal Muscular Atrophy (SMA, Types 2 and 3), Amyotrophic Lateral Sclerosis (ALS, upper limb-dominant), etc.
- Peripheral Neuropathies: Charcot-Marie-Tooth (CMT) disease, etc.
- Other Neuromuscular Conditions: Including but not limited to cervical spinal cord injury.
You likely can't join if
- Unwillingness or inability to provide informed consent.
- A score of 1 or 6 on the Brooke Upper Extremity Functional Rating Scale.
- Cognitive impairment severe enough to interfere with the proper use of a shoulder orthosis.
- Any other condition which, in the opinion of the investigator, would make study participation inappropriate or unsafe for the patient.
See the full eligibility criteria
- Patients with a confirmed diagnosis of a neuromuscular disease (NMD) by genetic testing, muscle biopsy, or electrodiagnostic studies, presenting with prominent upper limb muscle weakness. Examples include:
- Muscular Dystrophies: Duchenne/Becker Muscular Dystrophy (DMD/BMD), Limb-Girdle Muscular Dystrophy (LGMD), Facioscapulohumeral Muscular Dystrophy (FSHD), etc.
- Motor Neuron Diseases: Spinal Muscular Atrophy (SMA, Types 2 and 3), Amyotrophic Lateral Sclerosis (ALS, upper limb-dominant), etc.
- Peripheral Neuropathies: Charcot-Marie-Tooth (CMT) disease, etc.
- Other Neuromuscular Conditions: Including but not limited to cervical spinal cord injury.
- Aged over 10 years.
- A score of 2 to 5 on the Brooke Upper Extremity Functional Rating Scale.
- Manual Muscle Test (MMT) grade of less than 3 for shoulder abduction.
- Ability to provide written informed consent from the participant and/or their legal representative, indicating willingness to participate in the study.
- Unwillingness or inability to provide informed consent.
- A score of 1 or 6 on the Brooke Upper Extremity Functional Rating Scale.
- Cognitive impairment severe enough to interfere with the proper use of a shoulder orthosis.
- Any other condition which, in the opinion of the investigator, would make study participation inappropriate or unsafe for the patient.
The study team makes the final eligibility decision.
Where it's taking place
- Seoul, Jongno-gu, South Korea
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 10 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Seoul, Jongno-gu, South Korea. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.