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New treatment option for Hypoxemia
Official title Driving Pressure-guided Lung Protective Ventilation
ClinicalTrials.gov ID: NCT06361420
What this study is testing
- What it's testing
- The study, named as "The Efficacy of Driving Pressure-guided Lung Protective Ventilation in Surgical Repair of Acute Type A Aortic Dissection: an open-label, randomized control clinical trial", aims to investigate whether driving pressure-guided lung protective ventilation can reduce postoperative oxygenation function in patients who have undergone surgical repair of acute type A aortic dissection. The primary outcomes is the incidence of postoperative hypoxemia (a partial pressure of arterial oxygen to inspiratory oxygen fraction ratio less than 300 mm Hg or a peripheral blood oxygen saturation less than 93% at any concentration of inspiratory oxygen) within 7 days after the surgery.
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 14 to 70
You may be able to join if
- Able to sign Informed Consent and Release of Medical Information Forms;
- Age ≥ 14 years and ≤ 70 years old;
- Being confirmed the diagnosis by chest computed tomography angiography and receiving the surgical repair of acute type A aortic dissection.
You likely can't join if
- Age \ 70 years old;
- Sepsis before surgery;
- Chronic pulmonary disease including lung infection or asthma requiring long-term pharmacotherapy;
- History of lung tumor;
- Obstructive sleep apnea hypopnea syndrome requiring long-term noninvasive mechanical ventilation support;
- Heart failure requiring catecholamines or invasive mechanical ventilation support;
See the full eligibility criteria
- Able to sign Informed Consent and Release of Medical Information Forms;
- Age ≥ 14 years and ≤ 70 years old;
- Being confirmed the diagnosis by chest computed tomography angiography and receiving the surgical repair of acute type A aortic dissection.
- Age \ 70 years old;
- Sepsis before surgery;
- Chronic pulmonary disease including lung infection or asthma requiring long-term pharmacotherapy;
- History of lung tumor;
- Obstructive sleep apnea hypopnea syndrome requiring long-term noninvasive mechanical ventilation support;
- Heart failure requiring catecholamines or invasive mechanical ventilation support;
- Body mass index \> 30 Kg m-2;
- Being reluctance to participate this study.
The study team makes the final eligibility decision.
Where it's taking place
- Fuzhou, Fujian, China
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 14 years to 70 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Fuzhou, Fujian, China. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.