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New treatment option for Oxygenation Index
Official title Effects of Different Inhaled Oxygen Concentrations on Lung Function in Older Patients After Laparoscopic Gastrointestinal Surgery Under General Anesthesia
ClinicalTrials.gov ID: NCT06359106
What this study is testing
What is 80% Oxygen?
80% Oxygen is an investigational medicine, given as an inhaled treatment, being studied as a potential treatment for oxygenation index.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- This was a multicenter, prospective, parallel-grouping, randomized controlled clinical study comparing low FiO2 (40%) and high FiO2 (80%) levels in older patients undergoing laparoscopic gastrointestinal surgery.
- Phase 4: studies an already-approved treatment
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 65 and older
You may be able to join if
- Age not less than 65 years
- American Society of Anesthesiologists grades I-III
- No history of drug allergies or abnormal anesthesia.
- The duration of mechanical ventilation was expected to be more than 2 hours.
- Laparoscopic Gastrointestinal Surgery
You likely can't join if
- History of acute lung injury or acute respiratory distress syndrome (ARDS) within 3 months.
- Cardiac function Class IV (New York Heart Association classification)
- Chronic renal failure (renal cell filtration rate \<30 ml min-11.73/m2), severe liver disease
- Patients with blurred consciousness and cognitive dysfunction
- Severe coagulation dysfunction.
- Without preoperative oxygen inhalation, blood oxygen level \<94%, and severe pulmonary dysfunction
See the full eligibility criteria
- Age not less than 65 years
- American Society of Anesthesiologists grades I-III
- No history of drug allergies or abnormal anesthesia.
- The duration of mechanical ventilation was expected to be more than 2 hours.
- Laparoscopic Gastrointestinal Surgery
- The preoperative oxygen saturation was not less than 94%.
- The patients will be planned to extubate in the operating room.
- History of acute lung injury or acute respiratory distress syndrome (ARDS) within 3 months.
- Cardiac function Class IV (New York Heart Association classification)
- Chronic renal failure (renal cell filtration rate \<30 ml min-11.73/m2), severe liver disease
- Patients with blurred consciousness and cognitive dysfunction
- Severe coagulation dysfunction.
- Without preoperative oxygen inhalation, blood oxygen level \<94%, and severe pulmonary dysfunction
- Patients with endotracheal tubes were admitted to the intensive care unit (ICU) after surgery.
- Body mass index (BMI) \>30kg/m2
- Inability to complete the study
The study team makes the final eligibility decision.
Where it's taking place
- Shenyang, Liaoning, China
- Beijing, China
- Chendu, China
- Chifeng, China
- Dalian, China
- Harbin, China
- Jinan, China
- Kunming, China
- Qingdao, China
- Shenyang, China
- Shenzhen, China
- Shijia Zhuang, China
- Yanbian, China
Compensation & support
Compensation mentioned.
ClinicalTrials.gov doesn't provide a reliable structured field for payment or travel support - confirm details with the study team.
Questions & answers
Do participants get paid in this trial?
This study's listing includes signals that participants may be compensated or receive a stipend. Amounts vary and are set by the study team - confirm the details with them.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 65 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Shenyang, Liaoning, China; Beijing, China; Chendu, China; Chifeng, China; Dalian, China; Harbin, China and 7 more location(s). Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.