BridgeMD
New treatment option for Healthy Participants
Official title Rate of Tranexamic Acid Administration on Blood Pressure (RateTXA) Study.
ClinicalTrials.gov ID: NCT06356948
What this study is testing
What is Tranexamic Acid (TXA)?
Tranexamic Acid (TXA) is an investigational medicine, given as an infusion into a vein, being studied as a potential treatment for healthy participants.
Also referred to as Tranexamic Acid.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- Tranexamic acid is a well-established treatment for post-partum hemorrhage. This study aims to examine the effect of tranexamic acid administration rates on blood pressure changes over 1 minute compared to 10 minutes in healthy pregnant patients scheduled for cesarean delivery.
- Phase 4: studies an already-approved treatment
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 19 and older, women only. Healthy volunteers may be eligible.
You may be able to join if
- Pregnant patients ≥34 weeks gestational age, for elective cesarean delivery under single-shot spinal anesthesia.
- American Society of Anesthesiologists (ASA) Physical Status Class 2.
- Patients ≥19 years of age.
You likely can't join if
- Known history of pre-existing hypertension or hypertension disorders of pregnancy.
- Having recently taken a medication to treat high blood pressure (e.g. labetolol, hydralazine, nifedipine)
- Having recently taken a medication that could alter blood pressure, which could include beta those prescribed for anxiety (e.g. propranolol) or...
- Known allergic reaction or hypersensitivity to TXA or any other TXA homologue.
- Elective cesarean delivery requiring general anesthesia or a neuraxial technique other than a single-shot spinal (e.g. Epidural or Combined Spinal...
- Patients who are unable to give informed consent due to a language barrier as the study team only speaks English and will be unable to complete...
See the full eligibility criteria
- Pregnant patients ≥34 weeks gestational age, for elective cesarean delivery under single-shot spinal anesthesia.
- American Society of Anesthesiologists (ASA) Physical Status Class 2.
- Patients ≥19 years of age.
- Known history of pre-existing hypertension or hypertension disorders of pregnancy.
- Having recently taken a medication to treat high blood pressure (e.g. labetolol, hydralazine, nifedipine)
- Having recently taken a medication that could alter blood pressure, which could include beta those prescribed for anxiety (e.g. propranolol) or sedative pre-medication (e.g. midazolam, lorazepam).
- Known allergic reaction or hypersensitivity to TXA or any other TXA homologue.
- Elective cesarean delivery requiring general anesthesia or a neuraxial technique other than a single-shot spinal (e.g. Epidural or Combined Spinal Epidural).
- Patients who are unable to give informed consent due to a language barrier as the study team only speaks English and will be unable to complete consent process and study procedure appropriately.
- Patients arriving late to the surgical day care with \<90 min prior to scheduled cesarean delivery time resulting in potential delay for the operating room or inadequate time for consent and full execution of the...
The study team makes the final eligibility decision.
Where it's taking place
- Vancouver, British Columbia, Canada
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling female, 19 years and older. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Vancouver, British Columbia, Canada. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.