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Tests treatment safety and results for Schizophrenia; Negative Type
Official title An Open-Label, Single Arm Study of the Efficacy of Accelerated Intermittent Theta Burst Stimulation in Schizophrenia Patients With Persistent Negative Symptoms
ClinicalTrials.gov ID: NCT06351514
What this study is testing
- What it's testing
- Schizophrenia patients commonly present with persistent negative symptoms which remain the main reason for dysfunction after recovery from an acute episode of psychotic symptoms. Negative symptoms in schizophrenia exact significant burden with no effective pharmacological or behavior treatment options thus far.
- Phase 3: a large, late-stage study
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 21 to 65
You may be able to join if
- Age ≥21 and ≤65 years;
- With primary diagnosis of schizophrenia or schizoaffective disorder;
- Patients experienced prominent and persistent negative symptoms [Scale for the Assessment of Negative Symptoms (SANS) score ≥3 or Positive and...
- No clinically significant positive symptoms [PANSS positive subscale score \<20];
- No clinically significant depressive symptoms [Calgary Depression Scale for Schizophrenia (CDSS) score subscale \<12];
You likely can't join if
- With current misuse of or dependence on illegal drugs or alcohol;
- High Suicide risk;
- History of epileptic seizures;
- With severe brain trauma, injury or other neurological diseases;
- Metal (implants) in the skull;
- Pregnancy
See the full eligibility criteria
- Age ≥21 and ≤65 years;
- With primary diagnosis of schizophrenia or schizoaffective disorder;
- Patients experienced prominent and persistent negative symptoms [Scale for the Assessment of Negative Symptoms (SANS) score ≥3 or Positive and Negative Symptoms Scale (PANSS)- negative subscale score ≥20] in past 6...
- No clinically significant positive symptoms [PANSS positive subscale score \<20];
- No clinically significant depressive symptoms [Calgary Depression Scale for Schizophrenia (CDSS) score subscale \<12];
- Able to give consent.
- With current misuse of or dependence on illegal drugs or alcohol;
- High Suicide risk;
- History of epileptic seizures;
- With severe brain trauma, injury or other neurological diseases;
- Metal (implants) in the skull;
- Pregnancy
The study team makes the final eligibility decision.
Where it's taking place
- Singapore, Singapore
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 21 years to 65 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Singapore, Singapore. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.